Evidence map›Paper›PMID 40984829›Full record

Observational studyInternational health2026

The cost of dengue shock and septic shock in Vietnam: a patient-centred economic analysis.

Angela McBride, Nguyen Van Hao, Phan Vinh Tho, Luong Thi Hue Tai, Nguyen Thanh Phong, Nguyen Thanh Ngoc, Nguyen Anh Huyen, Trinh Manh Hung, Martin J Llewelyn, Sophie Yacoub and 2 more

Abstract readObservational Study
In one paragraph

Observational study in International health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Angela McBrideDepartment of Global Health and Infection, Brighton and Sussex Medical School, Brighton, UK, BN1 9PX.ORCID 0000-0002-5507-0415
Nguyen Van HaoHospital for Tropical Diseases, Ho Chi Minh City, Vietnam, 700000.
Phan Vinh ThoHospital for Tropical Diseases, Ho Chi Minh City, Vietnam, 700000.
Luong Thi Hue TaiHospital for Tropical Diseases, Ho Chi Minh City, Vietnam, 700000.
Nguyen Thanh PhongHospital for Tropical Diseases, Ho Chi Minh City, Vietnam, 700000.
Nguyen Thanh NgocDengue and Emerging Infection groups, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam, 700000.
Nguyen Anh HuyenDengue and Emerging Infection groups, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam, 700000.
Trinh Manh HungDengue and Emerging Infection groups, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam, 700000.
Martin J LlewelynDepartment of Global Health and Infection, Brighton and Sussex Medical School, Brighton, UK, BN1 9PX.
Sophie YacoubDengue and Emerging Infection groups, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam, 700000.ORCID 0000-0002-2910-7819
Louise ThwaitesDengue and Emerging Infection groups, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam, 700000.
Hugo C TurnerMRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London, UK, W12 0BZ.

Funding

Medical Research CouncilMedical Research Council (MRC)MRC Centre for Global Infectious Disease Analysis MR/X020258/1Wellcome Trust 106680Wellcome Trust 106680/B/14/ZWellcome Trust 203905Wellcome Trust 203905/Z/16/Z
6 · The paper itself

Abstract

backgroundDengue shock (DS) and septic shock (SS) are the most common infectious causes of shock in Vietnam. Little is known about the cost of an episode of DS or SS from the patient perspective. We aimed to describe the direct medical, non-medical and productivity costs associated with DS and SS.

methodsWe recruited adults with DS and SS to a prospective observational study at the Hospital for Tropical Diseases, Ho Chi Minh City, from 2019 to 2021. We collected hospital bills, insurance status and out of pocket payments, and conducted an economic questionnaire at discharge, 1, 3 and 6 mo later. We calculated the proportion incurring catastrophic health expenditure (CHE) and catastrophic costs.

resultsWe recruited 127 adults with DS, of whom 118 survived, and 35 with SS, of whom 24 survived; 18.9% and 71.4% with DS and SS, respectively, incurred CHE. When non-medical and productivity costs were considered, the true cost of illness was 6.3 and 6.7 times higher than the hospital bill for DS and SS, respectively.

conclusionsProductivity costs must be counted when assessing the cost of critical illness in low- and lower-middle income countries. It is vital that financial protection systems are extended to cover patients requiring high-cost critical care in Vietnam.

Indexed as

Cost of IllnessHealth ExpendituresSevere DengueShock, SepticAdultFemaleHumansMaleMiddle AgedProspective StudiesVietnamcatastrophic costscatastrophic health expenditureeconomicseptic shock, severe dengue, Vietnam

Identifiers

PMID40984829
PMCPMC7618728

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.