Evidence map›Paper›PMID 40984741›Full record

ArticleeLife2025

The increase in cell volume and nuclear number of the koji-fungus

Ayaka Itani, Haruto Motomura, Ken Oda, Hideyuki Yamashita, Kanae Sakai, Ken-Ichi Kusumoto, Shinsuke Shigeto, Takehiko Ichikawa, Hosain Mohammad Mubarak, Takeshi Fukuma and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. A phase oscillator model of cell cycles reveals nuclear density control in a branched fungal network.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ayaka ItaniMicrobiology Research Center for Sustainability (MiCS), Faculty of Life and Environmental Sciences, Tsukuba Institute for Advanced Research (TIAR), University of Tsukuba, Tsukuba, Japan.
Haruto MotomuraMicrobiology Research Center for Sustainability (MiCS), Faculty of Life and Environmental Sciences, Tsukuba Institute for Advanced Research (TIAR), University of Tsukuba, Tsukuba, Japan.
Ken OdaNational Research Institute of Brewing, Higashi-hiroshima, Japan.
Hideyuki YamashitaHiguchi Matsunosuke Shoten Co., Ltd., Osaka, Japan.
Kanae SakaiDepartment of Biotechnology, Graduate School of Engineering, Osaka University, Osaka, Japan.
Ken-Ichi KusumotoDepartment of Biotechnology, Graduate School of Engineering, Osaka University, Osaka, Japan.
Shinsuke ShigetoDepartment of Chemistry, School of Science, Kwansei Gakuin University, Hyogo, Japan.ORCID https://orcid.org/0000-0002-2035-2068
Takehiko IchikawaNano Life Science Institute (WPI-NanoLSI), Kanazawa University, Kanazawa, Japan.
Hosain Mohammad MubarakNano Life Science Institute (WPI-NanoLSI), Kanazawa University, Kanazawa, Japan.
Takeshi FukumaNano Life Science Institute (WPI-NanoLSI), Kanazawa University, Kanazawa, Japan.
Takuya KatayamaDepartment of Biotechnology, The University of Tokyo, Tokyo, Japan.
Jun-Ichi MaruyamaDepartment of Biotechnology, The University of Tokyo, Tokyo, Japan.
Shunsuke MasuoMicrobiology Research Center for Sustainability (MiCS), Faculty of Life and Environmental Sciences, Tsukuba Institute for Advanced Research (TIAR), University of Tsukuba, Tsukuba, Japan.ORCID https://orcid.org/0000-0002-0454-3315
Naoki TakayaMicrobiology Research Center for Sustainability (MiCS), Faculty of Life and Environmental Sciences, Tsukuba Institute for Advanced Research (TIAR), University of Tsukuba, Tsukuba, Japan.
Norio TakeshitaMicrobiology Research Center for Sustainability (MiCS), Faculty of Life and Environmental Sciences, Tsukuba Institute for Advanced Research (TIAR), University of Tsukuba, Tsukuba, Japan.ORCID https://orcid.org/0000-0003-2666-4991

Funding

Japan Science and Technology Agency 10.52926/jpmjer1502Ministry of Education, Culture, Sports, Science and Technology 21H02095Ministry of Education, Culture, Sports, Science and Technology 21K19062Ministry of Education, Culture, Sports, Science and Technology 22H04878Ministry of Education, Culture, Sports, Science and Technology 25K01927
6 · The paper itself

Abstract

While the ratio of nuclei to cell volume is well regulated, it remains largely unexplored in multinucleate organisms. The koji-fungus

Indexed as

Aspergillus oryzaeCell NucleusCell SizeFermentationFungal ProteinsHyphaeFungal ProteinsAspergillus oryzaecell volumeenzyme productionfermentationinfectious diseasekoji-fungusmicrobiologynuclei

Identifiers

PMID40984741
PMCPMC12456952

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.