Evidence map›Paper›PMID 40983844›Full record

ArticleObesity surgery2025

Sex Differences in Adiposity, Body Fat Mobilization and Cardiometabolic Health Following Bariatric Surgery.

Lajeunesse-Trempe Fannie, Laurie Marchand, Maëlle Blais, Audrey Auclair, Simon Marceau, Samuel Alarie, Paul Poirier, Marie-Ève Piché

Abstract read
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In one paragraph

Article in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lajeunesse-Trempe FannieInstitut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, Canada. fanny.lajeunesse-trempe.1@ulaval.ca.
Laurie MarchandInstitut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, Canada.
Maëlle BlaisInstitut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, Canada.
Audrey AuclairInstitut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, Canada.
Simon MarceauInstitut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, Canada.
Samuel AlarieInstitut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, Canada.
Paul PoirierInstitut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, Canada.
Marie-Ève PichéInstitut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, Canada. marie-eve.piche@criucpq.ulaval.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWeight loss in light of various weight management strategies, including bariatric surgery, is recognized to vary according to sex.

objectivesThis study aimed to compare sex differences in adiposity phenotypes, body fat mobilization, and obesity-associated comorbidities at baseline and after bariatric surgery.

methodsNinety patients (26 men and 64 women) who underwent biliopancreatic diversion with duodenal switch surgery (BPD-DS) were included. Medical history, anthropometric, and bioelectrical impedance measurements as well as computed tomography scans (CT scan) were performed at baseline and at 12-month after BPD-DS. Sex differences in post-operative fat and muscle mobilization were assessed using one-way analysis of variance.

resultsAt baseline, men (mean age 44.5 ± 13.2 years) presented a higher global lean mass, abdominal muscle (estimated using CT scan), a higher volume of abdominal visceral fat, and a larger proportion of mid-thigh muscle infiltrated with lipids; a proxy for ectopic fat deposition in skeletal muscle compared to women (p < 0.05 for all). After BPD-DS, there were no differences in fat distribution between sexes, except for abdominal fat volume and muscle infiltrated with lipids which remained higher in men (p < 0.05). These differences translated into a numerically non-significant lower rate of remission of comorbidities in men.

conclusionsOur result reports on sex differences in body fat mobilization at 12 months post-BPD-DS. Despite comparable body mass index and overall lean and fat mass, men exhibit a higher volume of abdominal fat volume and greater ectopic fat deposition in skeletal muscles compared to women.

Indexed as

Adipose TissueAdiposityBariatric SurgeryObesity, MorbidAdultBiliopancreatic DiversionBody CompositionFemaleHumansMaleMiddle AgedSex FactorsWeight Loss

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.