Trial reportAIDS and behavior2026
The Acceptability of a Real-Time Medication Monitoring-Based Digital Adherence Tool Among Young People Living with HIV in Malawi.
Trial report in AIDS and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Methamphetamine Use in People Living with HIV: Clinical, Neurocognitive, and Blood Biomarker Profiles.Biomedicines · 2026Article
- Interactive Internet-Based Motivational Interviewing Training for HIV Counseling Support Staff to Improve Health Communication in HIV Care Interactions: Protocol for Training Development and a Pilot Randomized Controlled Trial.JMIR research protocols · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
Adherence to antiretroviral therapy (ART) is required for young people living with HIV (YPLHIV, 15-24 years) to achieve viral suppression, prevent transmission, and reduce HIV-related morbidity and mortality. Real time medication monitoring based digital adherence tools (RTMM-DATs) - a combination of RTMMs (smart pillboxes), customised adherence feedback, SMS reminders, and optional alarms - may be used to provide promising interventions to improve ART adherence and viral suppression in YPLHIV. In this study, we sought to investigate the concurrent acceptability of a RTMM-DAT intervention which included RTMMs, customised adherence feedback, SMS reminders, and optional alarms, in non-adherent YPLHIV on ART in Malawi enrolled in a randomised controlled trial (RCT) to investigate the effect of the intervention on ART adherence and viral suppression. As a secondary objective, we explored barriers to ART adherence in YPLHIV using the intervention. We conducted a phenomenological study in fourteen YPLHIV enrolled in the intervention arm of the RCT for at least six months using semi-structured interviews between June and July 2024. The interview guide was structured around the constructs of the Theoretical Framework of Acceptability (TFA). Inductive and deductive thematic analysis were performed to achieve the objectives. Overall, the participants expressed positive attitudes toward the intervention and appreciated the portable and discreet design of the RTMM. They appreciated the intervention's usefulness in addressing forgetfulness and promoting routine medication use. Neutral SMS reminders and tailored adherence feedback were appreciated for promoting adherence while safeguarding privacy. Challenges included device recharging in settings with limited electricity, reliance on mobile phones for SMS reminders, lack of remote user access to adherence reports, potential unintended disclosure from audible alarms, and users' underlying social insecurities due to stigma. Furthermore, participants continued to face multiple and complex challenges to ART adherence, such as food insecurity, drug side effects, forgetfulness, and social stigma before and after engaging with the intervention. In conclusion, the intervention was generally acceptable among YPLHIV in Malawi. Addressing barriers such as electricity access, stigma, and enhancing user customisability and access to adherence reports could improve the intervention's acceptability. Additionally, tailoring the intervention to the socio-cultural context of YPLHIV is essential to improve acceptability.
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