Evidence map›Paper›PMID 40983742›Full record

ArticleAesthetic plastic surgery2026

Aesthetic and Psychosocial Impacts of Hyaluronic Acid Fillers in Patients with Retrognathic Profiles.

Luciana de Almeida Silva, Kleber Rosa de Almeida, Cristina Lúcia Feijó Ortolani

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Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Luciana de Almeida SilvaUniversidade Paulista (UNIP), São Paulo, Brazil. almeidadralu@gmail.com.ORCID 0000-0003-4077-9349
Kleber Rosa de AlmeidaUniversidade Paulista (UNIP), São Paulo, Brazil.ORCID 0000-0002-1621-9379
Cristina Lúcia Feijó OrtolaniUniversidade Paulista (UNIP), São Paulo, Brazil.ORCID 0000-0001-6854-6606

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study evaluated the effectiveness of hyaluronic acid (HA) in redefining the lower third of the face in orthodontically treated individuals with well-defined skeletal bases, focusing on its influence on facial aesthetics, self-esteem, and quality of life.

methodTwenty-four individuals aged 19-43 years with retruded chins participated in the study. Data collection included socioeconomic questionnaires and validated instruments such as the OHIP-14, Face-Q™, Rosenberg Self-Esteem Scale (RSES), and the Brazil-validated Orthognathic Quality-of-Life Questionnaire (B-OQLQ). Changes in perceived attractiveness were assessed through standardized pre- and post-treatment photographs. HA fillers, with rheological properties of high cohesiveness and elasticity, were applied to specific facial points based on the Medical Codes (MD Codes™) protocol. These points were strategically selected to project the chin, define the jawline, and improve the contours of the lower third of the face, using standardized techniques to achieve aesthetic harmony.

resultsA statistically significant improvement in satisfaction with the chin and jawline (p < 0.000755) was observed, accompanied by a substantial increase in perceived attractiveness after the treatment. A notable migration to lower B-OQLQ scores (< 10) indicated improvements in self-image and quality of life. Observers, including orthodontists, facial harmonizers, and laypeople, consistently rated post-treatment images as more aesthetically pleasing.

conclusionHA fillers demonstrated high efficacy in improving facial aesthetics, self-esteem, and quality of life in retrognathic patients post-orthodontic treatment. These findings support the use of HA as a minimally invasive alternative for facial enhancement. LEVEL OF EVIDENCE II: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors  www.springer.com/00266 .

Indexed as

Cosmetic TechniquesDermal FillersHyaluronic AcidQuality of LifeAdultEstheticsFemaleHumansMalePatient SatisfactionSelf ConceptSurveys and QuestionnairesTreatment OutcomeYoung AdultDermal FillersHyaluronic AcidChinHyaluronic acidPatient-reported outcome measuresQuality of lifeRetrognathia

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.