ArticleThe Journal of antibiotics2025
Linfuranone F, a PPARγ-agonistic furanone-containing polyketide, from a rare actinomycete Sphaerimonospora sp.
Article in The Journal of antibiotics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Linfuranone F (1), a new furanone-containing polyketide, was isolated from the culture extract of an actinomycete of the genus Sphaerimonospora along with three known linfuranones B (2), C (3), and D (4). Compound 1 was established as a 6,7-dehydrated congener of 3 by comparing their spectroscopic data and considering their biosynthetic relatedness. All compounds displayed agonistic activity against PPARγ in a reporter gene assay and 1 showed the highest activity.
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Registered trials
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