Evidence map›Paper›PMID 40983694›Full record

ArticleNature aging2025

Boosting astrocytic NAD

Zheng Chen, Seung-Hee Yoo

Abstract read
In one paragraph

Article in Nature aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zheng ChenDepartment of Biochemistry and Molecular Biology, McGovern Medical School, UT Health Science Center at Houston, Houston, TX, USA. Zheng.chen.1@uth.tmc.edu.ORCID http://orcid.org/0000-0002-2464-5474
Seung-Hee YooDepartment of Biochemistry and Molecular Biology, McGovern Medical School, UT Health Science Center at Houston, Houston, TX, USA. Seung-Hee.Yoo@uth.tmc.edu.ORCID http://orcid.org/0000-0002-9930-560X

Funding

Circadian regulation of mitochondrial function by muscle RORs to promote healthy agingR01AG089967 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Zheng Chen · 2024 to 2026
$2.5M
Concerted Enhancement Of Core And Output Rhythms To Promote Healthy AgingR01AG065984 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI CHEN, ZHENG · 2019 to 2023
$2.3M
Regulation of headache pain responses by the Trigeminal ganglion clockR01NS136677 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Mark J Burish, Seung-Hee Yoo · 2024 to 2026
$1.4M
NIA NIH HHS R01 AG065984NIA NIH HHS R01 AG089967NINDS NIH HHS R01 NS136677U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R01NS136677U.S. Department of Health & Human Services | NIH | National Institute on Aging (U.S. National Institute on Aging) R01AG065984
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40983694
PMCPMC13380838

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.