Evidence map›Paper›PMID 40983515›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2025

Prenatal Downregulation of CB

Samuel Simón-Sánchez, Femke den Boon, Daniel García-Rincón, Georgia Skrempou, Juan Paraíso-Luna, Alfonso Aguilera, Marta Nieto, Taco R Werkman, Manuel Guzmán, Pascal Chameau and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Samuel Simón-SánchezDepartment of Biochemistry and Molecular Biology, School of Chemistry, and Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, Madrid 28040, Spain.
Femke den BoonCellular and Computational Neuroscience, Center for Neurosciences, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1090 GE, Netherlands.
Daniel García-RincónDepartment of Biochemistry and Molecular Biology, School of Chemistry, and Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, Madrid 28040, Spain.
Georgia SkrempouCellular and Computational Neuroscience, Center for Neurosciences, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1090 GE, Netherlands.
Juan Paraíso-LunaDepartment of Biochemistry and Molecular Biology, School of Chemistry, and Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, Madrid 28040, Spain.ORCID 0000-0002-2176-4013
Alfonso AguileraDepartment of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CNB-CSIC), Madrid 28049, Spain.
Marta NietoDepartment of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CNB-CSIC), Madrid 28049, Spain.
Taco R WerkmanCellular and Computational Neuroscience, Center for Neurosciences, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1090 GE, Netherlands.
Manuel GuzmánDepartment of Biochemistry and Molecular Biology, School of Chemistry, and Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, Madrid 28040, Spain.
Pascal ChameauCellular and Computational Neuroscience, Center for Neurosciences, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1090 GE, Netherlands p.j.p.chameau@uva.nl igalvero@ucm.es.
Ismael Galve-RoperhDepartment of Biochemistry and Molecular Biology, School of Chemistry, and Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, Madrid 28040, Spain p.j.p.chameau@uva.nl igalvero@ucm.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endocannabinoid signaling exerts a neurodevelopmental regulatory role via CB

Indexed as

Down-RegulationPrefrontal CortexReceptor, Cannabinoid, CB1Social BehaviorAnimalsFemaleMaleMiceMice, Inbred C57BLPregnancyPyramidal CellsReceptor, Cannabinoid, CB1autismcannabinoidintellectual disabilityprefrontal cortexprojection neuronZBTB20

Identifiers

PMID40983515
PMCPMC12528840

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.