Evidence map›Paper›PMID 40983366›Full record

ArticleThe FEBS journal2026

D1/D5 receptor activation promotes long-term potentiation and synaptic tagging/capture in hippocampal area CA2.

Kevin Chua, Yee Song Chong, Sreedharan Sajikumar

Abstract read
In one paragraph

Article in The FEBS journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kevin ChuaDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.ORCID 0009-0009-3616-561X
Yee Song ChongDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.ORCID 0000-0003-2810-8585
Sreedharan SajikumarDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.ORCID 0000-0002-5761-8982

Funding

National Medical Research Council MOH-000641-00
6 · The paper itself

Abstract

Hippocampal area CA2 plays an important role in social memory formation. However, CA2 is characterised by plasticity-resistant Schaffer Collateral-CA2 (SC-CA2) synapses and highly plastic entorhinal cortex-CA2 (EC-CA2) synapses. Despite abundant dopaminergic input, the relationship between dopamine signalling and area CA2 synaptic plasticity remains unexplored. Here, we show that SKF-38393-mediated dopamine D1-like receptor (dopamine D

Indexed as

CA2 Region, HippocampalLong-Term PotentiationReceptors, Dopamine D1Receptors, Dopamine D5Synapses2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepineAnimalsCyclic AMP-Dependent Protein KinasesDopamine AgonistsMaleMiceNeuronal PlasticityRatsReceptors, N-Methyl-D-AspartateSignal Transduction2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepineCyclic AMP-Dependent Protein KinasesDopamine AgonistsReceptors, Dopamine D1Receptors, Dopamine D5Receptors, N-Methyl-D-AspartateCA2dopaminelong‐term potentiationmetaplasticitysocial memory

Identifiers

PMID40983366
PMCPMC12871914

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.