Evidence map›Paper›PMID 40983318›Full record

Trial reportClinical psychology & psychotherapy

The Predictive Value of Emotion Regulation in Cocaine Use Disorder Severity: Psychotherapeutic Implications During Hospitalization for Detoxification.

Alba Palazón-Llecha, Joan Trujols, Mercè Madre, Santiago Duran-Sindreu, Francesca Batlle, Núria Mallorquí-Bagué

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical psychology & psychotherapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05207228 (Randomized Clinical Trial), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05207228 naunknown statusnot on this map

Randomized Clinical Trial (RCT) for the Improvement of Cocaine Use Disorder Treatment Through the Implementation of a Cognitive Behavioral Therapy Web-based Treatment (CBT4CBT)

TypeinterventionalSponsorFundació Institut de Recerca de l'Hospital de la Santa Creu i Sant PauRan2021 to 2024Enrolled70ConditionsCocaine Use DisorderArmsCBT4CBT
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alba Palazón-LlechaDepartment of Psychology, Universitat de Girona (UdG), Girona, Spain.ORCID https://orcid.org/0009-0002-9174-5317
Joan TrujolsMental Health Institut de Recerca Sant Pau (IR Sant Pau), Barcelona, Spain.ORCID https://orcid.org/0000-0003-0396-7105
Mercè MadreMental Health Institut de Recerca Sant Pau (IR Sant Pau), Barcelona, Spain.ORCID https://orcid.org/0000-0002-4660-3216
Santiago Duran-SindreuMental Health Institut de Recerca Sant Pau (IR Sant Pau), Barcelona, Spain.ORCID https://orcid.org/0000-0002-8767-1821
Francesca BatlleMental Health Institut de Recerca Sant Pau (IR Sant Pau), Barcelona, Spain.ORCID https://orcid.org/0000-0002-8684-9579
Núria Mallorquí-BaguéDepartment of Psychology, Universitat de Girona (UdG), Girona, Spain.ORCID https://orcid.org/0000-0003-1434-3162

Funding

European Regional Development FundFundació Privada Hospital de la Santa Creu i Sant PauInstituto Carlos IIIInstituto de Salud Carlos III PI20/00929
6 · The paper itself

Abstract

objectiveTraditional treatment approaches in cocaine use disorder (CUD) still report high rates of poor outcomes. Emotion regulation (ER) is a transdiagnostic factor that may contribute to the initiation and maintenance of CUD, strengthening addiction severity. A deeper understanding of ER in this population is crucial for improving treatment outcomes. This study explores whether ER difficulties at treatment entry predict addiction severity and withdrawal symptom severity after discharge in patients with CUD. Secondarily, it examines whether withdrawal symptom severity mediates the relationship between ER difficulties and relapse.

methodsA total of 70 CUD patients underwent a 14-day inpatient detoxification. At admission, cocaine use-related variables and ER questionnaires (DERS and ERQ) were registered. After discharge, addiction severity (SDS), craving (WCS), cocaine withdrawal symptom severity (CSSA) and relapse were recorded. Multiple linear regression and mediation analysis were conducted to address the primary and secondary aims, respectively. This study draws on data from a larger randomized clinical trial.

resultsImpulse control difficulties and nonacceptance of emotional responses predicted SDS, and nonacceptance of emotional responses predicted CSSA. However, mediation analyses showed no indirect effect of DERS total score on relapse through the effect of the mediating variable CSSA.

conclusionER screening at hospitalization admission may optimize treatment by identifying high-risk CUD patients. Third-generation therapies targeting ER skills may enhance outcomes by helping patients manage emotional distress, potentially reducing addiction severity and withdrawal symptoms. Because of mixed results and the exploratory nature of this study, further research on the ER role in this context is needed.

trial registrationClinicalTrials.gov; ID: NCT05207228.

Indexed as

Cocaine-Related DisordersEmotional RegulationPsychotherapySubstance Withdrawal SyndromeAdultFemaleHospitalizationHumansMaleMiddle AgedRecurrenceSeverity of Illness Indexaddiction severitycocaine use disordercocaine withdrawal symptomsemotion regulationhospitalization

Identifiers

PMID40983318
PMCPMC12453906

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.