ArticleEnvironmental research2025
Prenatal air pollution exposure and placental vasculature development among participants of the UPSIDE cohort study.
Article in Environmental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Trimester-specific exposure to PMBMC pregnancy and childbirth · 2026Article
- PMAir quality, atmosphere, & health · 2025Article
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Authors and funding
17 authors.
Funding
Abstract
backgroundAir pollution exposure during pregnancy has been associated with reduced fetal growth and birth weight, but mechanisms mediating this association are not well understood.
objectivesWe examined whether pregnancy air pollution exposures were associated with altered placental vascularization.
methodsWe studied pregnant women (N = 163) from the UPSIDE cohort study, part of the Environmental Influences on Child Health Outcomes (ECHO) Study. Using placenta photographs taken at birth (gestational weeks 37-42), we derived seventeen chorionic plate surface vessel outcomes in 7 groups: arterial area, arterial branches, arterial arc length, arterial endpoint distance to perimeter, arterial branch angle, arterial tortuosity, and artery-vein distances. Distributed lag nonlinear models were used to determine if/when gestational week mean PM
resultsPlacental measures were more strongly associated with weekly NO
conclusionResidential traffic pollution exposure in early-pregnancy was associated with altered chorionic surface arterial vasculature, potentially leading to worse perfusion, while late-pregnancy positive associations may represent a compensatory response.
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