Evidence map›Paper›PMID 40982718›Full record

ArticleJBRA assisted reproduction2025

Toward clarity: why we need to standardize the term 'recurrent pregnancy loss'.

Luiza Pretto, Eduarda Nabinger, Ivan Sereno Montenegro, Maria Teresa Vieira Sanseverino, Osvaldo Artigalás, Fernanda Sales Luiz Vianna, Eduardo Pandolfi Passos, Lucas Rosa Fraga

Abstract readEditorial
In one paragraph

Article in JBRA assisted reproduction, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luiza PrettoUniversidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Eduarda NabingerUniversidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Ivan Sereno MontenegroHospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
Maria Teresa Vieira SanseverinoUniversidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Osvaldo ArtigalásHospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.
Fernanda Sales Luiz ViannaUniversidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Eduardo Pandolfi PassosUniversidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Lucas Rosa FragaUniversidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recurrent pregnancy loss (RPL) is a complex reproductive condition that remains difficult to manage. Despite advances in identifying risk factors and treating cases with known causes, about half of the cases are still idiopathic, making effective treatment and prognosis challenging. In addition to clinical hurdles, a major issue in both the literature and medical community is the lack of standardization in terminology and precise definition for RPL. Here, we review the main discrepancies in current definitions and support adopting the term 'recurrent pregnancy loss' as the most appropriate and inclusive. We recommend recognizing RPL as a specific subtype of secondary infertility, characterized by two or more pregnancy losses. Standardizing this terminology is crucial for improving diagnosis, research comparison, and patient care in reproductive medicine.

Indexed as

Abortion, HabitualTerminology as TopicFemaleHumansPregnancydefinition standardizationinfertilitymiscarriageterminology harmonization

Identifiers

PMID40982718
PMCPMC12469224

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.