Evidence map›Paper›PMID 40982155›Full record

ReviewMolecular biology reports2025

Quercetin and hematological cancers: where are we and where are we going?

Reza Arefnezhad, Abbas Alishahi, Mohadese Hematian, Aryan Rezaee, Alireza Khalilian, Farzad Nasrpour Tahouneh, Hassan Foroozand, Fatemeh Rezaei-Tazangi, Amirhossein Sahebkar, Ahmad Nazari

Abstract readReview
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In one paragraph

Review in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Reza ArefnezhadStudent Research Committee, Fasa University of Medical Sciences, Shiraz, Iran. Reza.aref1374@gmail.com.
Abbas AlishahiStudent Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.
Mohadese HematianSchool of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Aryan RezaeeStudent Research Committee, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Alireza KhalilianDepartment of Radiation Oncology, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Farzad Nasrpour TahounehDepartment of Clinical Pharmacy, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Hassan ForoozandStudent Research Committee, Fasa University of Medical Sciences, Shiraz, Iran.
Fatemeh Rezaei-TazangiDepartment of Anatomy, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran. f.rezaei67@yahoo.com.
Amirhossein SahebkarCenter for Global Health Research, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India. amir_saheb2000@yahoo.com.
Ahmad NazariTehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is recognized as a significant health challenge in the present era. Hematological cancers, including malignant lymphoma, leukemia, and multiple myeloma, are a group of malignancies associated with high morbidity and mortality. Despite efforts by researchers to improve medical knowledge, there still remains a need for efficient and safe therapeutic strategies. Plant-derived natural products have emerged as potential preventive and therapeutic options against various diseases including cancer. Quercetin, a bioactive flavonoid found in fruits and vegetables, possesses anti-neoplastic, anti-inflammatory, anti-oxidative, anti-bacterial, anti-viral, and anti-fungal properties. There is increasing evidence suggesting the therapeutic potential of quercetin against hematological neoplasms through different molecular and cellular mechanisms, such as influencing apoptosis and autophagy, angiogenesis, inflammation, and antioxidant system capacity. This review aims to explore the therapeutic effects and underlying mechanisms of action of quercetin against these cancers.

Indexed as

Hematologic NeoplasmsQuercetinAnimalsAntioxidantsApoptosisAutophagyHumansAntioxidantsQuercetinBioactive compoundLeukemiaMalignant lymphomaMultiple myelomaQuercetin

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.