ArticleNeuroscience bulletin2026
Effects of Stress Coping Styles and Social Defeat on Zebrafish Behaviour and Brain Transcriptomics.
Article in Neuroscience bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Cross-Species Social Experience Suppresses Aggression in Drosophila.Neuroscience bulletin · 2026Article
- Neurobehavioral Effects of Two Distinct Anti-Inflammatory Drugs in a Two-Week Chronic Stress Model in Zebrafish.Brain sciences · 2026Article
- Integrating behaviour, physiology, and immune response to social stress in fish.Frontiers in endocrinology · 2026Review
- Stress Coping Style Alters Functional Brain Network Activity to Acute Stressor.bioRxiv : the preprint server for biology · 2025Article
- Zebrafish as a Model Organism for Post-Traumatic Stress Disorder: Insights into Stress Mechanisms and Behavioral Assays.Biology · 2025Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Individuals with divergent personality traits corresponding to stress coping styles have been suggested to differ in behavioural and neural plasticity. We used a model of social defeat stress to assess the coping ability of wild zebrafish selectively bred for boldness/shyness. Behavioural tests were applied to assess parameters such as boldness/exploration, aggressiveness, and displacement behaviour. Gene expression changes in the brain were assessed via RNA sequencing. The main results show a strong effect of shyness and boldness phenotype on behaviour and the brain transcriptome. Fish of the shy line displayed significant behavioural differences, while the number of differentially-expressed genes remained low. In contrast, fish of the bold line exhibited a small effect on behaviour and pronounced changes in brain gene expression. This study highlights the importance of boldness phenotype and its influence on the response to social challenges at the behavioural and transcriptomic levels.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.