ArticleTropical animal health and production2025
Longitudinal study of antibody kinetics and vertical transmission of Toxoplasma gondii in naturally infected pregnant sheep in Brazil.
Article in Tropical animal health and production, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Toxoplasmosis is a reproductive disease with a significant impact on sheep farming, particularly when it affects pregnant ewes. However, there is still a lack of data regarding the humoral immune response in naturally infected animals, as well as information on the frequency of congenital transmission. In this context, the objective of this study was to report the vertical transmission rate of Toxoplasma gondii to lambs and the kinetics of anti-T. gondii antibodies in pregnant sheep. Fifteen infected ewes (Group 1, G1) and 45 non-infected ewes (Group 2, G2) were monitored through serological tests over a six-month period. At the end of the study, 46.7% (28/60) of the sheep were seroreactive, indicating a seroconversion rate of 28.9% (13/45) in G2. Vertical transmission was observed in 38.9% (7/18) of liveborn lambs and the overall abortion rate was 10.7% (3/28). Furthermore, a significant association was detected between maternal seropositivity and the transplacental transmission of T. gondii (p = 0.024). An increase in RIPC values in the ELISA was also observed prior to abortion in three ewes; however, no statistically significant differences were identified among the sampling days (p > 0.05). These findings highlight the importance of congenital transmission as an effective route of infection in lambs, in addition to indicating fluctuations in antibody titers during the gestation of naturally infected females. In this context, understanding the maternal immune response, particularly at critical stages of pregnancy, provides valuable insights into reproductive toxoplasmosis and the failures that lead to congenital infection.
Indexed as
Identifiers
40982071What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.