Evidence map›Paper›PMID 40982048›Full record

Trial reportEuropean journal of applied physiology2026

New Zealand blackcurrant extract has no effect on physiological and cardiovascular responses during low-intensity sustained intermittent isometric contractions in men.

Stefano Montanari, Ben J Lee, Sam D Blacker, Matthew D Cook, Mark E T Willems

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stefano MontanariInstitute of Applied Sciences, University of Chichester, College Lane, Chichester, PO19 6PE, UK.ORCID http://orcid.org/0009-0003-4906-8911
Ben J LeeInstitute of Applied Sciences, University of Chichester, College Lane, Chichester, PO19 6PE, UK.ORCID http://orcid.org/0000-0001-6826-7463
Sam D BlackerInstitute of Applied Sciences, University of Chichester, College Lane, Chichester, PO19 6PE, UK.ORCID http://orcid.org/0000-0003-3862-3572
Matthew D CookSchool of Sport and Exercise Science, University of Worcester, University of Worcester, Worcester, UK.ORCID http://orcid.org/0000-0002-6293-7566
Mark E T WillemsInstitute of Applied Sciences, University of Chichester, College Lane, Chichester, PO19 6PE, UK. m.willems@chi.ac.uk.ORCID http://orcid.org/0000-0003-4385-8739

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIntake of anthocyanin-rich supplements such as New Zealand blackcurrant (NZBC) extract for 7 days showed beneficial effects on cardiovascular function at rest and during moderate and high-intensity exercise. The effects of 4- and 7-day intake of 600 mg of NZBC extract on cardiovascular function, femoral artery diameter, muscle force, muscle activity and muscle fatigue during low-intensity sustained intermittent isometric contractions were examined.

methodsFifteen healthy males (age: 25 ± 6 years, height: 180 ± 7 cm, body mass: 82 ± 8 kg) visited the laboratory on five occasions (familiarisation, days 4 and 7 of placebo (PLA) or NZBC extract intake). Each visit required the participants to hold the isometric contraction of the m.quadriceps femoris at 10% of their isometric maximal voluntary contraction (iMVC) for 5 bouts of 2-min. At the end of each 2-min, an iMVC was performed with subsequent 20 s rest before starting a subsequent bout. Electromyography, isometric muscle force, hemodynamic and ultrasound data were recorded.

resultsAt days 4 and 7, there were no effects for NZBC extract on systolic blood pressure, diastolic blood pressure, heart rate, cardiac output, stroke volume, total peripheral resistance and femoral artery diameter. Although the isometric contraction protocol resulted in fatigue, there were no differences between PLA and NZBC extract conditions for isometric muscle force and muscle activity at days 4 and 7 (P > 0.05).

conclusionNZBC extract had no effect on cardiovascular function and exercise-induced fatigue during repeated bouts of low-intensity sustained intermittent isometric contractions of the m.quadriceps femoris, maybe due to the low demand of the exercise model.

Indexed as

Isometric ContractionPlant ExtractsRibesAdultBlood PressureFemoral ArteryHeart RateHumansMaleMuscle FatigueMuscle, SkeletalNew ZealandYoung AdultPlant ExtractsAnthocyaninsCardiovascular functionFemoral arteryIsometric forceLow-intensity contractionsNew Zealand blackcurrant

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.