Evidence map›Paper›PMID 40981415›Full record

ArticlemBio2025

The PAS domain of the polarly localized histidine kinase FlrB in

Venus Stanton, Bradley Himes, Adrian Mejia-Santana, Mark Eppinger, Jesus Romo, Jiawei Xing, Igor B Zhulin, Hong Cai, Yufeng Wang, Nicole L Inniss and 3 more

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Venus StantonSouth Texas Center for Emerging Infectious Diseases and Department of Molecular Microbiology and Immunology, University of Texas at San Antonio, San Antonio, Texas, USA.ORCID 0009-0003-9567-9051
Bradley HimesSouth Texas Center for Emerging Infectious Diseases and Department of Molecular Microbiology and Immunology, University of Texas at San Antonio, San Antonio, Texas, USA.
Adrian Mejia-SantanaSouth Texas Center for Emerging Infectious Diseases and Department of Molecular Microbiology and Immunology, University of Texas at San Antonio, San Antonio, Texas, USA.
Mark EppingerSouth Texas Center for Emerging Infectious Diseases and Department of Molecular Microbiology and Immunology, University of Texas at San Antonio, San Antonio, Texas, USA.
Jesus RomoSouth Texas Center for Emerging Infectious Diseases and Department of Molecular Microbiology and Immunology, University of Texas at San Antonio, San Antonio, Texas, USA.ORCID 0000-0002-1683-2288
Jiawei XingDepartment of Microbiology, Translational Data Analytics Institute, The Ohio State University, Columbus, Ohio, USA.
Igor B ZhulinDepartment of Microbiology, Translational Data Analytics Institute, The Ohio State University, Columbus, Ohio, USA.
Hong CaiSouth Texas Center for Emerging Infectious Diseases and Department of Molecular Microbiology and Immunology, University of Texas at San Antonio, San Antonio, Texas, USA.
Yufeng WangSouth Texas Center for Emerging Infectious Diseases and Department of Molecular Microbiology and Immunology, University of Texas at San Antonio, San Antonio, Texas, USA.
Nicole L InnissDepartment of Microbiology-Immunology and Center for Structural Biology of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0002-1510-7412
George MinasovDepartment of Microbiology-Immunology and Center for Structural Biology of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Karla J F SatchellDepartment of Microbiology-Immunology and Center for Structural Biology of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0003-3274-7611
Karl E KloseSouth Texas Center for Emerging Infectious Diseases and Department of Molecular Microbiology and Immunology, University of Texas at San Antonio, San Antonio, Texas, USA.ORCID 0000-0003-2007-1407

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Devalingam Mahalingam · 1993 to 2026
$153.9M
TO PROVIDE SCIENTIFIC SUPPORT TO THE CENTERS FOR RESEARCH ON STRUCTURAL BIOLOGY OF INFECTIOUS DISEASES.75N93022C00035 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SATCHELL, KARLA · 2022 to 2025
$20.7M
Computational Genomics of Signal TransductionR35GM131760 · NIGMS · OHIO STATE UNIVERSITY · PI Igor B. Jouline · 2019 to 2026
$3.2M
Michigan Economic Development Corporation 085P1000817NCI NIH HHS P30 CA060553NIAID NIH HHS 75N93022C00035NIGMS NIH HHS R35 GM131760U.S. Department of Energy DE-AC02-06CH11357
6 · The paper itself

Abstract

IMPORTANCE:

Indexed as

Bacterial ProteinsFlagellaGene Expression Regulation, BacterialHistidine KinaseIntestinesProtein KinasesTranscription, GeneticVibrio choleraeAnimalsCholeraCrystallography, X-RayFlagellinMicePhosphorylationProtein DomainsBacterial ProteinsFlagellinHistidine KinaseProtein Kinasescholeraflagellar motilitypathogenesissignal transductionsubcellular localizationtranscriptional regulation

Identifiers

PMID40981415
PMCPMC12607845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.