Evidence map›Paper›PMID 40981300›Full record

ArticleInternational journal of neonatal screening2025

Evaluating the Impact of Newborn Screening for Cystic Fibrosis in Portugal: A Decade of Insights and Outcomes.

Bernardo Camacho, Luísa Pereira, Raquel Bragança, Susana Castanhinha, Raquel Penteado, Teresa R Silva, Pedro Miragaia, Sónia Silva, Ana L Cardoso, Telma Barbosa and 6 more

Abstract read
In one paragraph

Article in International journal of neonatal screening, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Bernardo CamachoDepartment of Paediatrics, Hospital Dr. Nélio Mendonça, 9000-177 Funchal, Portugal.ORCID 0000-0001-9414-3560
Luísa PereiraCystic Fibrosis Reference Centre, Department of Paediatrics, Hospital Santa Maria, Unidade Local de Saúde Santa Maria, 1649-035 Lisbon, Portugal.
Raquel BragançaCystic Fibrosis Reference Centre, Department of Paediatrics, Hospital Dona Estefânia, Unidade Local de Saúde de São José, 1169-045 Lisbon, Portugal.
Susana CastanhinhaCystic Fibrosis Reference Centre, Department of Paediatrics, Hospital Dona Estefânia, Unidade Local de Saúde de São José, 1169-045 Lisbon, Portugal.ORCID 0000-0003-0762-7730
Raquel PenteadoCystic Fibrosis Reference Centre, Department of Paediatrics, Hospital Pediátrico, Unidade Local de Saúde de Coimbra, 3000-602 Coimbra, Portugal.ORCID 0000-0002-8939-3861
Teresa R SilvaCystic Fibrosis Reference Centre, Department of Paediatrics, Hospital Pediátrico, Unidade Local de Saúde de Coimbra, 3000-602 Coimbra, Portugal.
Pedro MiragaiaDepartment of Paediatrics, Hospital de São João, Unidade Local de Saúde São João, 4200-319 Porto, Portugal.ORCID 0009-0008-7263-2353
Sónia SilvaCystic Fibrosis Reference Centre, Department of Paediatrics, Hospital de São João, Unidade Local de Saúde São João, 4200-319 Porto, Portugal.
Ana L CardosoCystic Fibrosis Reference Centre, Department of Paediatrics, Centro Materno Infantil do Norte, Unidade Local de Saúde Santo António, 4050-651 Porto, Portugal.ORCID 0000-0002-1575-5006
Telma BarbosaCystic Fibrosis Reference Centre, Department of Paediatrics, Centro Materno Infantil do Norte, Unidade Local de Saúde Santo António, 4050-651 Porto, Portugal.
Cristina FreitasDepartment of Paediatrics, Hospital Dr. Nélio Mendonça, 9000-177 Funchal, Portugal.
Juan GonçalvesDepartment of Paediatrics, Hospital Divino Espírito Santo, 9500-370 Ponta Delgada, Portugal.
Ana MarcãoNeonatal Screening Unit, National Institute of Health Dr Ricardo Jorge, 1649-016 Porto, Portugal.ORCID 0000-0001-8549-166X
Laura VilarinhoNeonatal Screening Unit, National Institute of Health Dr Ricardo Jorge, 1649-016 Porto, Portugal.ORCID 0000-0001-6186-779X
Celeste BarretoCystic Fibrosis Reference Centre, Department of Paediatrics, Hospital Santa Maria, Unidade Local de Saúde Santa Maria, 1649-035 Lisbon, Portugal.
Carolina ConstantCystic Fibrosis Reference Centre, Department of Paediatrics, Hospital Santa Maria, Unidade Local de Saúde Santa Maria, 1649-035 Lisbon, Portugal.ORCID 0000-0002-6596-1596

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The implementation of newborn screening (NBS) has revolutionized the diagnostic landscape of cystic fibrosis (CF). In Portugal, NBS was initiated in October 2013 through a pilot study and was subsequently fully integrated into a nationwide program by December 2018. Infants with positive screening results are referred to a specialized CF reference center for diagnostic confirmation, employing Sweat Chloride Testing (SCT) and genetic testing for

Indexed as

cystic fibrosisfalse negativesnewborn screeningpositive predictive valuesensitivity

Identifiers

PMID40981300
PMCPMC12452577

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.