Evidence map›Paper›PMID 40981187›Full record

ArticleMedical sciences (Basel, Switzerland)2025

Outcomes of Kidney Transplantation from Deceased Donors with Severe Acute Kidney Injury (AKIN Stage 3): A Preliminary Single-Centre Analysis.

Juan A Encarnación, Elisabeth Coll, Clara Manso, Santiago Llorente, Francisco Morales, Isabel Saura, Pedro López-Cubillana, Pablo Luis Guzman Martínez-Valls, Gloria Martínez, Isabel De la Fuente and 6 more

Abstract read
In one paragraph

Article in Medical sciences (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Juan A EncarnaciónDepartment of Radiation Oncology, Virgen de la Arrixaca University Clinical Hospital, 30120 Murcia, Spain.ORCID 0000-0003-1463-9326
Elisabeth CollNational Transplant Organization (ONT), 28049 Madrid, Spain.
Clara MansoMurcian Institute of Biosanitary Research, 30120 Murcia, Spain.
Santiago LlorenteDepartment of Nephrology, Virgen de la Arrixaca University Clinical Hospital, 30120 Murcia, Spain.ORCID 0000-0002-4933-8243
Francisco MoralesDepartment of Nephrology, Virgen de la Arrixaca University Clinical Hospital, 30120 Murcia, Spain.
Isabel SauraDepartment of Nephrology, Virgen de la Arrixaca University Clinical Hospital, 30120 Murcia, Spain.
Pedro López-CubillanaDepartment of Urology, Virgen de la Arrixaca University Clinical Hospital, 30120 Murcia, Spain.
Pablo Luis Guzman Martínez-VallsDepartment of Urology, Virgen de la Arrixaca University Clinical Hospital, 30120 Murcia, Spain.ORCID 0000-0001-5847-7248
Gloria MartínezDepartment of Urology, Virgen de la Arrixaca University Clinical Hospital, 30120 Murcia, Spain.
Isabel De la FuenteDepartment of Radiation Oncology, Virgen de la Arrixaca University Clinical Hospital, 30120 Murcia, Spain.
Enrique CárdenasDepartment of Radiation Oncology, Virgen de la Arrixaca University Clinical Hospital, 30120 Murcia, Spain.
Jose L Alonso-RomeroMurcian Institute of Biosanitary Research, 30120 Murcia, Spain.ORCID 0000-0001-8746-2096
Paula RuizMurcian Institute of Biosanitary Research, 30120 Murcia, Spain.
José MoyaTransplant Coordination, Virgen de la Arrixaca University Clinical Hospital, 30120 Murcia, Spain.
Beatriz Domínguez-GilNational Transplant Organization (ONT), 28049 Madrid, Spain.
Mario Royo-VillanovaMurcian Institute of Biosanitary Research, 30120 Murcia, Spain.ORCID 0000-0002-2898-2312

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe shortage of donor kidneys has prompted interest in using organs from donors with severe acute kidney injury (AKI), but robust data on outcomes from donors with AKIN stage 3 remain limited.

methodsThis single-centre, retrospective cohort study compared outcomes of kidney transplants from deceased donors with AKIN stage 3 AKI to matched non-AKI donors (

resultsDGF occurred in 54.4% (31/57) of AKIN 3 recipients vs. 33.3% (19/57) of non-AKI recipients (risk difference 21.1%, 95% CI 3.1-39.2;

conclusionsIn this preliminary, selected kidneys from AKIN stage 3 donors yielded similar medium-term graft and patient survival to non-AKI donors, despite higher DGF incidence. Findings should be interpreted cautiously and confirmed in adequately powered, multicentre studies with extended follow-up.

Indexed as

Acute Kidney InjuryKidney TransplantationTissue DonorsAdultDelayed Graft FunctionFemaleGraft SurvivalHumansMaleMiddle AgedRetrospective StudiesRisk FactorsTreatment Outcomeacute kidney injuryAKIN 3delayed graft functiondonor selectiongraft survivalkidney transplantation

Identifiers

PMID40981187
PMCPMC12452455

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.