Evidence map›Paper›PMID 40980927›Full record

ArticleInfection and immunity2025

Elevated glucose increases

Emily M Hughes, Meghan J Hirsch, Joshua T Huffines, Stefanie Krick, Megan R Kiedrowski

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Microbial and host innate immune factors affecting the persistence ofFrontiers in cellular and infection microbiology · 2026
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Emily M HughesDivision of Pulmonary, Allergy and Critical Care, Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0003-3085-902X
Meghan J HirschDivision of Pulmonary, Allergy and Critical Care, Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Joshua T HuffinesDivision of Pulmonary, Allergy and Critical Care, Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Stefanie KrickDivision of Pulmonary, Allergy and Critical Care, Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Megan R KiedrowskiDivision of Pulmonary, Allergy and Critical Care, Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0003-4610-182X

Funding

UAB Center for Clinical and Translational Sciences (CCTS)TL1TR001418 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SAAG, KENNETH G · 2015 to 2018
$2.1M
Cystic Fibrosis Foundation KIEDRO18F5NCATS NIH HHS TL1 TR001418NIH HHS 5TL1TR001418
6 · The paper itself

Abstract

In a healthy lung, the airway epithelium regulates glucose transport to maintain low glucose concentrations in the airway surface liquid (ASL). However, hyperglycemia and chronic lung diseases, such as cystic fibrosis (CF), can result in increased glucose in bronchial aspirates. People with CF are also at increased risk of lung infections caused by bacterial pathogens, including methicillin-resistant

Indexed as

Cystic FibrosisDrug Resistance, BacterialEpithelial CellsGlucoseStaphylococcal InfectionsStaphylococcus aureusAnti-Bacterial AgentsCell LineHumansHyperglycemiaMethicillin-Resistant Staphylococcus aureusRespiratory MucosaAnti-Bacterial AgentsGlucoseantibiotic resistancebacterial aggregationbiofilmCF-related diabetescystic fibrosisStaphylococcus aureus

Identifiers

PMID40980927
PMCPMC12519781

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.