Evidence map›Paper›PMID 40980919›Full record

ArticleAntimicrobial agents and chemotherapy2025

Epetraborole pharmacokinetics/pharmacodynamics in the hollow fiber system model of

Sanjay Singh, Megan Devine, Tawanda Gumbo, Shashikant Srivastava

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sanjay SinghDivision of Infectious Diseases, Department of Medicine, University of Texas at Tyler School of Medicine, Tyler, Texas, USA.ORCID 0000-0003-4601-5673
Megan DevineDepartment of Medicine, Section of Pulmonary and Critical Care, University of Texas at Tyler School of Medicine, Tyler, Texas, USA.ORCID 0000-0003-3279-1110
Tawanda GumboMathematical Modeling and AI Department, Praedicare Inc., Dallas, Texas, USA.ORCID 0000-0001-7592-8012
Shashikant SrivastavaDivision of Infectious Diseases, Department of Medicine, University of Texas at Tyler School of Medicine, Tyler, Texas, USA.ORCID 0000-0002-8786-8851

Funding

Short course combination regimens for treatment of Mycobacterium avium pulmonary disease: a translational bench-to-bedside approachR01AI179827 · NIAID · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI Shashi Kant · 2024 to 2026
$1.7M
PK/PD Optimized Cephalosporins Based Treatment Regimens for Children With MDR-TBR01HD099756 · NICHD · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI KANT, SHASHI · 2019 to 2023
$1.6M
Reinforcing old warriors to treat Mycobacterium kansasii in shorter durationR21AI148096 · NIAID · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI KANT, SHASHI · 2020 to 2021
$413k
Eunice Kennedy Shriver National Institute of Child Health and Human Development 1R01HD099756National Institute of Allergy and Infectious Diseases 1R01AI179827National Institute of Allergy and Infectious Diseases 1R21AI148096NIAID NIH HHS R01 AI179827NIAID NIH HHS R21 AI148096NICHD NIH HHS R01 HD099756
6 · The paper itself

Abstract

In the hollow fiber system model of tuberculosis (TB), the ratio of area under the concentration-time curve to MIC (AUC

Indexed as

Antitubercular AgentsMycobacterium tuberculosisArea Under CurveHumansMicrobial Sensitivity TestsMonte Carlo MethodTuberculosisAntitubercular Agentsclinical trial simulationsepetraboroleM. tuberculosismultidrug-resistancepharmacodynamicspharmacokinetics

Identifiers

PMID40980919
PMCPMC12587543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.