Evidence map›Paper›PMID 40980889›Full record

ArticlemBio2025

Unveiling immune interference: how the dendritic cell response to co-infection with

Linda Heilig, Lydia Bussemer, Lea Strobel, Kerstin Hünniger-Ast, Oliver Kurzai, Arnhild Grothey, Lars Dölken, Kerstin Laib Sampaio, Gianni Panagiotou, Alexander J Westermann and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. First Case of Concurrent Cytomegalovirus andInfection and drug resistance · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Linda Heilig *Department of Internal Medicine II, University Hospital Wuerzburg, Wuerzburg, Germany.ORCID 0009-0004-2255-5178
Lydia Bussemer *Department of Internal Medicine II, University Hospital Wuerzburg, Wuerzburg, Germany.
Lea StrobelDepartment of Internal Medicine II, University Hospital Wuerzburg, Wuerzburg, Germany.
Kerstin Hünniger-AstInstitute for Hygiene und Microbiology, University of Wuerzburg, Wuerzburg, Germany.
Oliver KurzaiInstitute for Hygiene und Microbiology, University of Wuerzburg, Wuerzburg, Germany.
Arnhild GrotheyInstitute for Virology, Hannover Medical School, Hannover, Germany.
Lars DölkenInstitute for Virology, Hannover Medical School, Hannover, Germany.ORCID 0000-0002-4651-3544
Kerstin Laib SampaioInstitute for Virology, Ulm University Medical Center, Ulm, Germany.
Gianni PanagiotouFaculty of Biological Sciences, Friedrich Schiller University, Jena, Germany.
Alexander J WestermannHelmholtz Institute for RNA-based Infection Research, Helmholtz Centre for Infection Research, Wuerzburg, Germany.
Hermann EinseleDepartment of Internal Medicine II, University Hospital Wuerzburg, Wuerzburg, Germany.
Sebastian Wurster *Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0002-7784-7256
Sascha Schäuble *Department of Microbiome Dynamic, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute (HKI), Jena, Germany.
Jürgen Löffler *Department of Internal Medicine II, University Hospital Wuerzburg, Wuerzburg, Germany.ORCID 0000-0001-6619-1100

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human cytomegalovirus (HCMV) is a master of immune evasion and a potent modulator of the human immune system. The best-characterized mechanism employed by HCMV to suppress host immunity is the production of a viral interleukin-10 homolog (

Indexed as

AspergillosisAspergillus fumigatusCoinfectionCytomegalovirusDendritic CellsImmune EvasionInterleukin-10Viral ProteinsCytokinesHost-Pathogen InteractionsHumansCytokinesIL10 protein, humanInterleukin-10Viral ProteinsaspergillosisCMVIL-10co-infectiondendritic cellshuman cytomegalovirus (HCMV)immune interferenceimmune suppressionimmunomodulation

Identifiers

PMID40980889
PMCPMC12607784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.