Evidence map›Paper›PMID 40980755›Full record

ArticleArXiv2025

Hopfield Networks as Models of Emergent Function in Biology.

Maria Yampolskaya, Pankaj Mehta

Abstract readPreprint
In one paragraph

Article in ArXiv, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Maria YampolskayaDepartment of Physics, Boston University, Boston, MA, USA, 02215.
Pankaj MehtaDepartment of Physics, Boston University, Boston, MA, USA, 02215.

Funding

MODELING EMERGENT BEHAVIORS IN SYSTEMS BIOLOGY: A BIOLOGICAL PHYSICS APPROACHR35GM119461 · NIGMS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI Pankaj Mehta · 2016 to 2026
$3.6M
NIGMS NIH HHS R35 GM119461
6 · The paper itself

Abstract

Hopfield models, originally developed to study memory retrieval in neural networks, have become versatile tools for modeling diverse biological systems in which function emerges from collective dynamics. In this review, we provide a pedagogical introduction to both classical and modern Hopfield networks from a biophysical perspective. After presenting the underlying mathematics, we build physical intuition through three complementary interpretations of Hopfield dynamics: as noise discrimination, as a geometric construction defining a natural coordinate system in pattern space, and as gradient-like descent on an energy landscape. We then survey recent applications of Hopfield networks a variety of biological setting including cellular differentiation and epigenetic memory, molecular self-assembly, and spatial neural representations.

Indexed as

cellular differentiationHopfield modelmodern Hopfield networksself-assembly

Identifiers

PMID40980755
PMCPMC12447707

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.