ArticleFrontiers in bioinformatics2025
Adaptive sampling methods facilitate the determination of reliable dataset sizes for evidence-based modeling.
Article in Frontiers in bioinformatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- DataXflowGen for GenAI-driven model generation.Scientific reports · 2026Article
- Mathematical strategies for predicting resistant subpopulations from scRNAseq data of a PANC-1 3D tissue model: Insight into gemcitabine resistance and TGFB1-induced invasion and EMT.Computational and structural biotechnology journal · 2025Article
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Abstract
How can we be sure that there is sufficient data for our model, such that the predictions remain reliable on unseen data and the conclusions drawn from the fitted model would not vary significantly when using a different sample of the same size? We answer these and related questions through a systematic approach that examines the data size and the corresponding gains in accuracy. Assuming the sample data are drawn from a data pool with no data drift, the law of large numbers ensures that a model converges to its ground truth accuracy. Our approach provides a heuristic method for investigating the speed of convergence with respect to the size of the data sample. This relationship is estimated using sampling methods, which introduces a variation in the convergence speed results across different runs. To stabilize results-so that conclusions do not depend on the run-and extract the most reliable information encoded in the available data regarding convergence speed, the presented method automatically determines a sufficient number of repetitions to reduce sampling deviations below a predefined threshold, thereby ensuring the reliability of conclusions about the required amount of data.
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