Trial reportOpen forum infectious diseases2025
Costs of 4 Months of Rifampin Versus 2 Months of Double-dose Rifampin for Tuberculosis Infection: Post-Hoc Analysis of a Phase 2b Randomized Trial.
Trial report in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Cost is an important consideration when implementing tuberculosis preventive treatment regimens (TPT). We used data from a phase 2b randomized trial of TPT to estimate overall cost and key drivers of costs for two TPT regimens. Methods: We did a post-hoc analysis of 915 participants aged ≥10 years who were randomized 1:1 to 2 rifampin-based regimens: a four-month daily regimen at 10 mg/kg (4R Results: Overall, 454 participants received 4R Conclusions: Most costs associated with TPT are due to medications and the baseline treatment initiation visit. TPT regimens requiring fewer follow-up visits may reduce overall cost, but the magnitude of this reduction varies by country.
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