Evidence map›Paper›PMID 40980560›Full record

ArticleOrthopaedic journal of sports medicine2025

Comparative Clinical and Imaging Outcomes of Particulated Juvenile Articular Cartilage Implantation in Shouldered and Unshouldered Patellar Cartilage Lesions With Concomitant Stabilization at 2-Year Follow-up.

Ryann Davie, Brittany Ammerman, Bennett Propp, Erick Marigi, William Marmor, Natalie Pahapill, Kiera Kingston, Simone Gruber, Alissa Burge, Audrey Wimberly and 3 more

Abstract read
In one paragraph

Article in Orthopaedic journal of sports medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ryann DavieHospital for Special Surgery, New York, USA.
Brittany AmmermanHospital for Special Surgery, New York, USA.
Bennett ProppHospital for Special Surgery, New York, USA.
Erick MarigiMayo Clinic, Rochester, Minnesota, USA.
William MarmorUniversity of Miami, Miami, Florida, USA.ORCID https://orcid.org/0000-0002-8434-2088
Natalie PahapillHospital for Special Surgery, New York, USA.
Kiera KingstonEndeavor Health, Evanston, Illinois, USA.
Simone GruberHospital for Special Surgery, New York, USA.
Alissa BurgeHospital for Special Surgery, New York, USA.
Audrey WimberlyHospital for Special Surgery, New York, USA.
Joseph NguyenHospital for Special Surgery, New York, USA.ORCID https://orcid.org/0000-0003-1686-3911
Elizabeth DennisMount Sinai Hospital, Brooklyn, New York, USA.ORCID https://orcid.org/0000-0002-7214-3460
Beth E Shubin SteinHospital for Special Surgery, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Particulated juvenile articular cartilage (PJAC) implantation has demonstrated promising early results in the treatment of symptomatic articular cartilage defects of the patella. However, some uncertainty exists regarding the stability of this cell-based technique in lesions that are not well contained or shouldered. Purpose: To compare clinical and magnetic resonance imaging (MRI) outcomes of PJAC treatment in shouldered versus unshouldered full-thickness cartilage defects of the patella. Study Design: Cohort study; Level of evidence, 3. Methods: A retrospective review of prospectively collected data from an institutional knee registry was conducted to identify patients treated with PJAC for full-thickness symptomatic patellar cartilage lesion between January 2009 and August 2017. Cartilage defects were graded arthroscopically according to the Outerbridge classification and characterized as shouldered or unshouldered. For the primary outcome, postoperative MRI studies were read by a musculoskeletal fellowship-trained radiologist who characterized the percentage of fill based on both coronal and sagittal images. Patient-reported outcome measures (PROMs) were obtained at baseline and 2-year follow-up. MRI and PROM results were compared between the shouldered and unshouldered cohorts. Results: A total of 64 knees in 60 patients (mean age, 26.3 ± 7.6 years) were identified, of which 62 (97%) knees underwent a concomitant patellar stabilization or offloading procedure. There were 32 (50%) shouldered and 32 (50%) unshouldered defects. On postoperative MRI, 68.8% of shouldered lesions demonstrated 67% to 100% fill, compared with 59.4% of unshouldered lesions; 12.5% of shouldered lesions and 15.6% of unshouldered lesions demonstrated 34% to 66% fill; and 18.8% of shouldered lesions and 25.0% of unshouldered lesions demonstrated 0% to 33% fill ( Conclusion: PJAC implantation with concomitant patellar stabilization led to significantly improved PROMs for both shouldered and unshouldered patellar cartilage lesions over time. Additionally, minimal differences were observed between shouldered and unshouldered defects treated with PJAC at the 2-year follow-up.

Indexed as

cartilage repairkneemagnetic resonance; allograftsMPFL reconstructionparticulated juvenile articular cartilagepatella; articular cartilage resurfacing; imagingpatellar instabilitypatellofemoraltibial tubercle osteotomy

Identifiers

PMID40980560
PMCPMC12444055

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.