Evidence map›Paper›PMID 40980538›Full record

ArticleInternational journal of nanomedicine2025

ROS-Sensitive MgOSiO

Yu Zheng, Zhouxiaolong Zhang, Yingna Cui, Na Liu, Hongting Ma, Benjie Wang, Ruixin Li, Nan Zhu, Nan Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of nanomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yu Zheng *Department of Orthopedics, The Affiliated Xinhua Hospital of Dalian University, Dalian, Liaoning Province, People's Republic of China.
Zhouxiaolong Zhang *School of Chemistry, Dalian University of Technology, Dalian, Liaoning Province, People's Republic of China.
Yingna CuiSchool of Chemistry, Dalian University, Dalian, Liaoning Province, People's Republic of China.
Na LiuDepartment of Orthopedics, The Affiliated Xinhua Hospital of Dalian University, Dalian, Liaoning Province, People's Republic of China.ORCID 0000-0002-3391-6969
Hongting MaSchool of Chemistry, Dalian University of Technology, Dalian, Liaoning Province, People's Republic of China.
Benjie WangDepartment of Orthopedics, The Affiliated Xinhua Hospital of Dalian University, Dalian, Liaoning Province, People's Republic of China.
Ruixin LiDepartment of Orthopedics, The Affiliated Xinhua Hospital of Dalian University, Dalian, Liaoning Province, People's Republic of China.
Nan ZhuSchool of Chemistry, Dalian University of Technology, Dalian, Liaoning Province, People's Republic of China.
Nan ZhangDepartment of Orthopedics, The Affiliated Xinhua Hospital of Dalian University, Dalian, Liaoning Province, People's Republic of China.ORCID 0000-0002-6441-8022

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Magnesium oxide nanoparticles (MgO NPs) as magnesium ionophores have shown potential as a therapeutic strategy for osteoarthritis. However, the rapid absorption and clearance of MgO NPs in the joint cavity and the lack of a clear underlying mechanism may limit their therapeutic efficacy. Methods: MgO@SiO Results: MgO@SiO Conclusion: As a multi-functional ROS-responsive nanosystem, MgO@SiO

Indexed as

Magnesium OxideNanocapsulesOsteoarthritisReactive Oxygen SpeciesSilicon DioxideAnimalsCell SurvivalChondrocytesDelayed-Action PreparationsDisease Models, AnimalMaleOxidative StressRatsRats, Sprague-DawleyDelayed-Action PreparationsMagnesium OxideNanocapsulesReactive Oxygen SpeciesSilicon Dioxideantioxidative stressMgO@SiO2 nanocapsulesosteoarthritisROS-responsive nanosystem

Identifiers

PMID40980538
PMCPMC12445432

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.