Evidence map›Paper›PMID 40980433›Full record

ArticleMethodsX2025

Protocol- Comprehensive Care Package to reduce deaths among adult persons diagnosed with Tuberculosis in Kerala, India (CCp-K)-An implementation project.

Raman Swathy Vaman, Kalaiselvi Selvaraj, Dina Nair, Abey Sushan, Aparna Mohan, Krishna Devadhas Sulochana, Jeen Melfha, Arun Paramarthalingom Vijayalekshmi, Vyas Sukumaran, Naveen Anaswara and 5 more

Abstract read
In one paragraph

Article in MethodsX, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Raman Swathy VamanDepartment of Health and Family Welfare, Government of Kerala, India.
Kalaiselvi SelvarajAll India Institute of Medical Sciences, Madurai, Tamil Nadu, India.
Dina NairICMR- National Institute for Research in Tuberculosis, Chennai, Tamil Nadu, India.
Abey SushanDepartment of Health and Family Welfare, Government of Kerala, India.
Aparna MohanWHO NTEP division, Kerala, India.
Krishna Devadhas SulochanaDepartment of Health and Family Welfare, Government of Kerala, India.
Jeen MelfhaICMR- National Institute of Epidemiology, Chennai, Tamil Nadu, India.
Arun Paramarthalingom VijayalekshmiDepartment of Health and Family Welfare, Government of Kerala, India.
Vyas SukumaranDepartment of Health and Family Welfare, Government of Kerala, India.
Naveen AnaswaraDepartment of Health and Family Welfare, Government of Kerala, India.
Sujith SukumaranDepartment of Health and Family Welfare, Government of Kerala, India.
Annadurai JeyakumarICMR- National Institute of Epidemiology, Chennai, Tamil Nadu, India.
Rakesh Purushothama Bhat SusheelaThe Union, New Delhi, India.
Rajaram KizhakkekandiyilDepartment of Health and Family Welfare, Government of Kerala, India.
Hemant Deepak ShewadeICMR- National Institute of Epidemiology, Chennai, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This implementation project aims to reduce TB mortality by at least 25% through early triaging and integrated management of co-morbidities in Kerala, India. The package will be implemented across Kerala's public health facilities, targeting all adult TB patients for systematic triaging for severe illness, uncontrolled diabetes mellitus, alcohol dependence, and tobacco dependence. Triage-positive individuals will be referred for comprehensive assessment and inpatient care to nodal treatment centres. This research will follow a mixed-methods approach with quantitative components assessing feasibility, burden, and programmatic outcomes, and qualitative interviews exploring facilitators and barriers. Triaging will be integrated into routine workflows with healthcare worker training and system monitoring using customized indicators. If found feasible and effective in improving programmatic outcomes such as early triaging and inpatient referral, this model offers potential for scale-up across India to reduce preventable TB deaths through differentiated care and targeted comorbidity management. • Implements a comprehensive care package to reduce TB deaths through early triaging and comorbidity management • Leverages existing public health infrastructure to deliver enhanced TB care within routine programme settings.

Indexed as

Differentiated TB careImplementation researchIndiaOperational researchTB mortalityTuberculosis

Identifiers

PMID40980433
PMCPMC12446617

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.