ArticlePakistan journal of medical sciences2025
Assisted reproduction outcome of the cases with male factor infertility: A retrospective chart review of 1913 ICSI cycles along 10 years.
Article in Pakistan journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: The aim of this study was to compare assisted reproduction outcome of couples with male factor and unexplained infertility. Methods: This study is ten years of retrospective chart review of 1913 ICSI cycles performed at ART unit of a tertiary center between 2014-2023. Patients who underwent IVF due to the diagnosis of male factor infertility were included in study group (n=560). Those with unexplained infertility were added as controls (n=1353). Groups were compared in terms of cycle outcome. Results: Female age revealed significantly higher in control group (32.2 vs 31.0,p<0.001), while no significant difference was observed between the groups among male. While higher number of Grade-1 embryos were utilized in male factor group on 2 Conclusions: Intrastoplasmic sperm injection provided worse results in progession from clevage stage to blastocycst formation in cases with male factor infertility. Analysis revealed that pregnancy outcome was significantly associated with total sperm motility. Sperm concentration was significantly associated with number of day five top-quality embryos.
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