ReviewFrontiers in microbiology2025
Bioactivity of microbial biofilms in extreme environments.
Review in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Diverse biosynthetic pathways in Arctic hydrothermal biofilms.Nature communications · 2026Article
- Microbial exopolysaccharides in environmental remediation: production, mechanisms, and challenges.Folia microbiologica · 2026Review
- Can Bacterial Manipulation Deliver Reef-Scale Thermal Enhancement of Corals?Microorganisms · 2026Review
- Life resists chemistry not conditions.FEMS microbes · 2026Article
- Simultaneous real-time imaging of oxygen gradients and in vivo microbial community spatial organization in confined environments.ISME communications · 2026Article
- Cloning and Characterization of the Novel Endoglucanase Identified in Deep Subsurface Thermal Well of Biragzang (North Ossetia) by Metagenomic Analysis.Biomolecules · 2025Article
- Surviving desiccation: key factors underlying tolerance in prokaryotes and eukaryotes.Protoplasma · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biofilms, which are highly structured microbial communities encased in a self-produced matrix, are frequently employed by many bacteria and archaea with significant implications for their survival in extreme environments. These environments, characterized by extreme temperatures, pH, salinity, and variable nutrient availability, can pose challenges that biofilms help organisms overcome through unique adaptations. This review explores the bioactivity of biofilms in extreme environments, highlighting biofilms' ability to produce novel biomolecules and other biofunctions with potential applications in medicine and biotechnology. Key adaptations such as extracellular polymeric substances, cooperative and competitive interactions, and specialized nutrient acquisition strategies are examined for their roles in biofilm resilience and bioactivity. The potential of these biofilms to contribute to the development of novel therapeutics, antimicrobial agents, antioxidants, and anticancer compounds is discussed, underscoring their significance in advancing medical and biotechnological applications. Through an in-depth analysis of current knowledge, this review highlights the bioactive capacities of extremophilic biofilms and their promising applications for human benefit.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.