Evidence map›Paper›PMID 40980301›Full record

ArticleWorld journal of diabetes2025

Income and wealth inequality is associated with young-onset type 2 diabetes.

Fu-Shun Yen, James Cheng-Chung Wei, Yao-Min Hung, Jia-Sin Liu, Chii-Min Hwu, Chih-Cheng Hsu

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Article in World journal of diabetes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Fu-Shun YenDr. Yen's Clinic, Taoyuan 330, Taiwan.
James Cheng-Chung WeiDepartment of Allergy, Immunology and Rheumatology, Chung Shan Medical University Hospital, Taichung 40201, Taiwan.
Yao-Min HungDepartment of Internal Medicine, Taitung Hospital, Taitung 95043, Taiwan.
Jia-Sin LiuNational Health Research Institutes, Miaoli 35053, Taiwan.
Chii-Min HwuSection of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Chih-Cheng HsuNational Center for Geriatrics and Welfare Research, Institute of Population Health Sciences, National Health Research Institutes, Miaoli 35053, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are only a few studies on the influence of economic inequalities on young-onset type 2 diabetes (T2D).

aimTo examine the impact of different family incomes on the development of young-onset T2D.

methodsWe identified 7505336 young adults aged 20-39 years from the 2008 Taiwan National Health Insurance Research Database. The young adults were divided into low-income, middle-income, and high-income groups. Cox proportional hazards models were used to determine the risks of young-onset T2D and all-cause mortality in low-income and middle-income groups compared with the high-income group.

resultsWith a mean follow-up of 8.0 years, the incidence rates of young-onset T2D were 3.39, 3.10, and 2.88 per 1000 person-years in the low-income, middle-income, and high-income groups, respectively. Compared with the high-income group, the risk of young-onset T2D was significantly higher in the low-income [adjusted hazard ratio (aHR) (95%CI): 1.46 (1.44-1.48)] and middle-income [aHR (95%CI): 1.29 (1.27-1.31)] groups. All-cause mortality was also higher in the low-income [aHR (95%CI): 2.79 (2.70-2.88)] and middle-income [aHR (95%CI): 1.59 (1.53-1.65)] groups. Older age, male sex, obesity, smoking, alcohol-related disorders, hypertension, dyslipidemia, gout, and psychotic disorders were significantly associated with increased risks of both young-onset T2D and mortality.

conclusionThis nationwide cohort study demonstrated that young people from low-income and middle-income groups had a higher risk of youth-onset T2D and mortality than those from the high-income group.

Indexed as

All-cause mortalityFamily incomeHigh-incomeLow-incomeMiddle-incomeYoung-onset diabetesYoung-onset type 2 diabetes

Identifiers

PMID40980301
PMCPMC12444305

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.