ArticleWorld journal of diabetes2025
Magnetic resonance imaging derived biomarkers for the diagnosis of type 2 diabetes with insulin resistance: A pilot study.
Article in World journal of diabetes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Potentially novel surrogate biomarker for diagnosing insulin resistance in type 2 diabetes.World journal of diabetes · 2025Article
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7 authors.
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Abstract
backgroundInsulin resistance (IR) plays a critical role in the musculoskeletal metabolic disorders associated with type 2 diabetes mellitus (T2DM).
aimTo develop multiparametric magnetic resonance imaging (MRI)-derived biomarkers and diagnostic models for non-invasive identification and stratification of IR.
methodsParameters of paravertebral muscles and vertebra were evaluated using quantitative chemical shift-encoded MRI and diffusion tensor imaging protocols. Tripartite cohort analyses were conducted through Kruskal-Wallis
resultsThis study evaluated 97 subjects (control: 39 subjects, T2DM-IR: 18 subjects, T2DM patients without IR: 40 subjects) using multiparametric MRI protocols. Significant intergroup differences were observed in the cross-sectional area (
conclusionIMCL in erector emerges as a highly discriminative metric for T2DM-IR diagnosis. Multiparametric MRI enables non-invasive quantification of early musculoskeletal metabolic injury, providing reliable biomarkers for IR identification and stratification.
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