Evidence map›Paper›PMID 40980256›Full record

ArticleResearch and practice in thrombosis and haemostasis2025

Skeletal muscle oxygenation and fluid content in upper extremity postthrombotic syndrome: a proof-of-concept study.

Laura Avila, Scott Thomas, Athena Mancini, Gina Wong, Brenna Wong, Leonardo R Brandão, Angelika Stavrakoukas, Leigh Ward, Robert F Bentley

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Article in Research and practice in thrombosis and haemostasis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laura AvilaChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.
Scott ThomasFaculty of Kinesiology and Physical Education, University of Toronto, Toronto, Ontario, Canada.
Athena ManciniChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.
Gina WongChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.
Brenna WongChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.
Leonardo R BrandãoDivision of Haematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Angelika StavrakoukasChild Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.
Leigh WardSchool of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, Brisbane, Queensland, Australia.
Robert F BentleyFaculty of Kinesiology and Physical Education, University of Toronto, Toronto, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Little is known about the pathophysiology of upper extremity (UE) postthrombotic syndrome (PTS). Objectives: We aimed to investigate the effect of PTS severity on UE muscle oxygen saturation (SmO Methods: Eleven cases with unilateral or bilateral UE-PTS who sustained deep vein thrombosis (DVT) in childhood, and 11 age- and sex-matched controls from the general population were recruited for this case-control study. PTS was measured using CAPTSure (0-100-point score). SmO Results: Median age of DVT diagnosis among cases was 5.6 years (quartile [Q]1-Q3, 0.2-16.1 years). At the time of the study, median CAPTSure score in the DVT-affected UE was 39 points (Q1-Q3, 27-55 points); 55% of DVTs were associated with a central venous catheter. Mixed models showed that increasing PTS severity was associated with lower SmO Conclusion: The lower SmO

Indexed as

adolescentexercise testnear-infrared spectroscopyvenous thrombosisyoung adult

Identifiers

PMID40980256
PMCPMC12447999

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.