ArticleArthroscopy, sports medicine, and rehabilitation2025
Soaking in Povidone-Iodine, Chlorhexidine, Teicoplanin, Vancomycin, and Saline Solution Differentially Alters Porcine Flexor Tendon Size and Biomechanical Properties.
Article in Arthroscopy, sports medicine, and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Chlorhexidine as the optimal disinfection method for an accidentally dropped autograft during an anterior cruciate ligament reconstruction surgery: A double-blind study.Journal of experimental orthopaedics · 2026Article
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Authors and funding
4 authors.
Funding
Abstract
Purpose: To compare the impact of povidone-iodine, chlorhexidine, vancomycin, and teicoplanin on the size and biomechanical properties of porcine flexor tendon grafts. Methods: Porcine deep digital flexor tendons (N = 120) were collected in pairs and allocated into povidone-iodine, chlorhexidine, vancomycin, teicoplanin, and saline solution groups (12 pairs per solution). The tendons from one side underwent a 30-minute soaking in these solutions, whereas those from the other side were wrapped in saline solution-soaked gauze. Tendon cross-sectional area (CSA) was measured before and after soaking, along with unsoaked controls. Tensile testing to failure was performed. Stiffness, load at failure, modulus, and stress at failure were calculated. Results: Soaking in povidone-iodine and chlorhexidine decreased the average CSA by 8% (-0.9 mm Conclusions: Soaking porcine flexor tendons in povidone-iodine and chlorhexidine resulted in a decrease in CSA, whereas soaking in vancomycin and teicoplanin led to an increase, similar to saline solution. No significant side-to-side differences in average CSA were observed. Soaking in chlorhexidine decreased stiffness but increased stress at failure. None of the solutions affected load at failure. Clinical Relevance: It is important to understand the impact of soaking porcine flexor tendon grafts in various antimicrobial solutions to ensure that there are no harmful biomechanical effects to the tissues used in the clinical setting.
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Registered trials
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