Evidence map›Paper›PMID 40980141›Full record

ArticleClinical, cosmetic and investigational dermatology2025

Successful Treatment of Childhood Nail Lichen Planus with Ruxolitinib Cream: A Case Report.

Anqi Sheng, Wenting Hu, Ai'e Xu

Abstract readCase Reports
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anqi ShengDepartment of Dermatology, Hangzhou Third People's Hospital, Hangzhou, Zhejiang, People's Republic of China.
Wenting HuDepartment of Dermatology, Hangzhou Third People's Hospital, Hangzhou, Zhejiang, People's Republic of China.ORCID 0000-0003-4639-9056
Ai'e XuDepartment of Dermatology, Hangzhou Third People's Hospital, Hangzhou, Zhejiang, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of oral JAK inhibitors in the treatment of nail lichen planus (NLP) has recently been reported, but there have been no literature reports on the treatment of NLP with topical Janus kinase (JAK) inhibitor. We present, for the first time, a preliminary clinical experience with topical ruxolitinib cream, a JAK inhibitor, in a child with NLP. The remarkable results suggest topical ruxolitinib cream may be a potential treatment option for NLP.

Indexed as

childJanus kinase inhibitornail lichen planusruxolitinib cream

Identifiers

PMID40980141
PMCPMC12445295

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.