ArticleFrontiers in pediatrics2025
Hepatitis B vaccination coverage rates among under-five children in India: a systematic review and meta-analysis protocol.
Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Asian Burden of Liver Cancer 1990-2021 and Predictions to 2040: An Analysis of the Global Burden of Disease Study 2021.Cancer control : journal of the Moffitt Cancer CenterArticle
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Hepatitis B virus (HBV) affects an estimated 1.5 million people globally each year, with nearly 296 million living with chronic infection, contributing significantly to cirrhosis, liver cancer, and premature mortality. Despite the availability of a highly effective vaccine, hepatitis B remains endemic in many low- and middle-income countries, including India, due to barriers in healthcare access and low vaccination uptake. While a timely birth dose prevents perinatal transmission, completion of the full vaccine schedule is essential to prevent horizontal transmission-a major mode of infection in India. India introduced the hepatitis B vaccine in select districts in 2002-2003 and scaled it nationally through the Universal Immunization Programme in 2011-2012. Objective: This systematic review and meta-analysis aims to estimate the pooled coverage of hepatitis B vaccination among children under 5 years of age across different regions of India. Methods and analysis: A comprehensive literature search will be conducted using PubMed, Embase, and CINAHL databases to identify studies published between 1 January 2000 and 30 May 2024. The search terms will include "Hepatitis B," "vaccination coverage," "children," and "India," combined using Boolean operators. Two independent reviewers will screen titles, abstracts, and full-text articles for eligibility. The AXIS tool will be used to assess the quality of cross-sectional studies. Pooled coverage rates will be estimated using a random-effects meta-analysis model. Heterogeneity will be assessed using the
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