Evidence map›Paper›PMID 40979954›Full record

ArticleRSC advances2025

A highly sensitive photoelectrochemical immunosensor for cancer antigen (CA 125) based on a nanoplatform of carbon dots and cadmium sulphide.

Ezinne U Ekwujuru, Cornelius C Ssemakalu, Michael J Klink, Moses G Peleyeju

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ezinne U EkwujuruDepartment of Natural Sciences, Vaal University of Technology Vanderbijlpark 1911 South Africa mosesp@vut.ac.za mgpeleyeju@gmail.com.
Cornelius C SsemakaluDepartment of Natural Sciences, Vaal University of Technology Vanderbijlpark 1911 South Africa mosesp@vut.ac.za mgpeleyeju@gmail.com.
Michael J KlinkDepartment of Natural Sciences, Vaal University of Technology Vanderbijlpark 1911 South Africa mosesp@vut.ac.za mgpeleyeju@gmail.com.
Moses G PeleyejuDepartment of Natural Sciences, Vaal University of Technology Vanderbijlpark 1911 South Africa mosesp@vut.ac.za mgpeleyeju@gmail.com.ORCID https://orcid.org/0000-0002-2941-3728

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prognosis for ovarian cancer is often poor due to late diagnosis. This is because the disease rarely presents with any specific symptoms in the early stage. There is therefore a need to develop a sensitive device for the routine screening of CA 125, the most widely used biomarker for detecting and monitoring ovarian malignancy. Herein, we report the development of a photoelectrochemical (PEC) immunosensor based on a screen-printed carbon electrode (SPCE) modified with a carbon nanodot/cadmium sulphide (CND/CdS) heterostructure for the sensitive detection of CA 125. Using a drop-casting technique and a self-assembly process, the immunosensor was constructed by the successive immobilization of CND, CdS, an

Identifiers

PMID40979954
PMCPMC12447262

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.