ReviewBurns & trauma2025
Role of oxidative stress in post-burn wound healing.
Review in Burns & trauma, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Probiotics and Extracellular Vesicles as Redox Modulators in Wound Healing: From Microbial Therapeutics to Engineered Nanotherapeutic Strategies.Antioxidants (Basel, Switzerland) · 2026Review
- Article
- Burn-associated metabolic dysfunction: could extracellular vesicles play a role?Clinical science (London, England : 1979) · 2026Review
- Internal gelation-based alginate hydrogel films incorporating Quercus infectoria gall extract for multifunctional wound dressing applications.Scientific reports · 2026Article
- The Role and Mechanism of Nanozymes in Burn Wound Healing.International journal of nanomedicine · 2026Review
- A novel collagen hydrogel loaded with primary brown sugar for accelerating burn wound healing by a synergistic mechanism.Regenerative biomaterials · 2026Article
- ROS-responsive drug delivery systems for chronic wound healing: advances, challenges, and translational perspectives.Military Medical Research · 2026Review
- Beyond wound closure: translational opportunities and barriers of mesenchymal stem cells and their extracellular vesicles in burn management.Frontiers in cell and developmental biology · 2026Review
- Advanced Hydrogel Functionalization Strategies for Burn-Related Wound Treatment.Biomaterials research · 2026Review
- Burns in Early Childhood: Age-Specific Causes, Risks, Management, and Implications-A Narrative Review.Children (Basel, Switzerland) · 2025Review
- Preventive and Therapeutic Effects of Hydrogen-Generating Si-Based Agent on Pressure Ulcers in Mice.Biomedicines · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oxidative stress is an inherent pathophysiological feature in burn wound healing. Severe burns trigger rapid changes in patients' conditions, leading to ischemia-reperfusion injury from early fluid resuscitation, neuroendocrine stress, and fluid imbalances, which exacerbate oxidative damage and organ dysfunction. This review highlights the critical role of oxidative stress in post-burn wound healing, its potential to cause cellular and tissue damage, and oxidative stress mechanisms. Antioxidant therapy is recommended as a cost-effective method of modulating inflammation and burn outcome. Preparative measures of successful antioxidant therapy should be developed in improving burn patients' wound healing.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.