Evidence map›Paper›PMID 40979775›Full record

ArticleIndian journal of anaesthesia2025

Analgesic efficacy of ultrasound-guided genicular nerve block in combination with adductor canal block in total knee arthroplasty: A randomised, double-blind, placebo-controlled trial.

Rajendra K Sahoo, Laxman K Senapati, Prateek Mitra, Ganesh C Satapathy, Abhijit S Nair, Priyadarsini Samanta

Abstract read
In one paragraph

Article in Indian journal of anaesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rajendra K SahooDepartment of Pain and Palliative Medicine, Kalinga Institute of Medical Sciences, KIIT Deemed to be University, Bhubaneswar, Odisha, India.ORCID https://orcid.org/0000-0002-9489-0694
Laxman K SenapatiDepartment of Anaesthesiology, Kalinga Institute of Medical Sciences, KIIT Deemed to be University, Bhubaneswar, Odisha, India.ORCID https://orcid.org/0000-0002-8727-4412
Prateek MitraDepartment of Anaesthesiology, Kalinga Institute of Medical Sciences, KIIT Deemed to be University, Bhubaneswar, Odisha, India.ORCID https://orcid.org/0009-0001-9047-8205
Ganesh C SatapathyDepartment of Anaesthesiology, Kalinga Institute of Medical Sciences, KIIT Deemed to be University, Bhubaneswar, Odisha, India.ORCID https://orcid.org/0009-0009-1271-8961
Abhijit S NairDepartment of Anaesthesiology, Ibra Hospital, Sultanate of Oman.ORCID https://orcid.org/0000-0003-2506-0301
Priyadarsini SamantaDepartment of Physiology, Kalinga Institute of Medical Sciences, KIIT Deemed to be University, Bhubaneswar, Odisha, India.ORCID https://orcid.org/0000-0001-9220-4059

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Distal motor-sparing nerve blocks are increasingly popular for knee arthroplasty pain. Genicular nerve ablation, initially proposed for knee osteoarthritis, is also currently used for postoperative pain management. We hypothesised that superior postoperative analgesia can be achieved by combining genicular nerve block with adductor canal block (ACB) by reducing 24-hour opioid consumption. Methods: Fifty patients were assigned to Group I (ultrasound-guided ACB with 20 mL of 0.25% ropivacaine and 4 mg dexamethasone and ultrasound-guided superomedial (SM), superolateral (SL), and inferomedial (IM) GNB with 5 mL of 0.25% ropivacaine and 2 mg of dexamethasone at each location and Group II (ultrasound-guided ACB with 20 mL of 0.25% ropivacaine, 4 mg dexamethasone, and ultrasound-guided three-location GNB with 15 mL of 0.9% saline). The outcomes measured were 24-hour morphine consumption, pain scores over 24 hours, and the time to rescue analgesia. The continuous data were analysed using an unpaired Results: The mean total consumption of morphine (mg) was 5.96 [standard deviation (SD): 2.73] in Group I and 15.52 (SD: 2.67) in Group II, with a mean difference of 9.56 [95% confidence interval (CI): -4.66, -2.39] ( Conclusion: Combining genicular block with ACB provided superior postoperative analgesia and reduced opioid consumption compared to ACB alone.

Indexed as

Adductor canal blockanalgesiagenicular nerve blockkneeknee osteoarthritisnerve blockpainpostoperative painregional anaesthesiatotal knee arthroplastyultrasound

Identifiers

PMID40979775
PMCPMC12445763

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.