ArticleJCPP advances2025
Validation of CBCL depression scores of adolescents in three independent datasets.
Article in JCPP advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- The topology of adolescent mental health.medRxiv : the preprint server for health sciences · 2026Article
- Longitudinal associations between depressive symptoms and brain structure across late childhood and adolescence: A panel network analysis study.medRxiv : the preprint server for health sciences · 2026Article
- The Dyadic Context of Preadolescent Girls' Depressive Symptoms: Elucidating The Role of Biobehavioral Synchrony.Journal of child and family studies · 2026Article
- Brief report: joint trajectories of anxiety and depression symptoms in an inception cohort of autistic youth.Frontiers in psychiatry · 2026Article
- Article
- Validation of CBCL depression scores of adolescents in three independent datasets.JCPP advances · 2025Article
- Environmentally derived subgroups of preadolescents with family history of substance use exhibit distinct patterns of psychopathology and reward-related behaviors: insights from the ABCD study.Frontiers in child and adolescent psychiatry · 2025Article
- Psychiatric Symptoms, Cognition, and Symptom Severity in Children.JAMA psychiatry · 2024Article
- Article
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4 authors.
Funding
Abstract
Background: Depression is common, burdensome, and is frequently first diagnosed in adolescents. The popular Adolescent Brain Cognitive Development dataset (ABCD) provides an attractive opportunity to research depression in adolescents. The only continuous measure of depression, as defined by DSM-5, in ABCD is the Child Behavior Checklist's DSM-5-Oriented Affective Problems scale (CBCL-Aff). We validated CBCL-Aff in the ABCD data and confirmed our results on two independent datasets: the Healthy Brain Network (HBN) and the Brazilian High Risk Cohort Study (BHRC). Methods: We tested Sensitivity, Specificity and Strict Specificity. Our participants were aged 8-11 years (ABCD) or 8-12 years (HBN, BHRC). Sample size was 183-1189 participants, depending on the analysis. Sample sizes and positive case ratios were established from power estimations. We evaluated goodness of prediction with AUCROCs. Results: In ABCD with parent-report diagnoses, CBCL-Aff had the AUCROC value of 0.95 in the Sensitivity and 0.87 in the Specificity analysis. In ABCD with child-report diagnoses, CBCL-Aff had the AUCROC of 0.62 (Sensitivity), 0.48 (Specificity) and 0.46 (Strict Specificity). In HBN and BHRC, CBCL-Aff successfully predicted clinician-report diagnoses (HBN Sensitivity: AUCROC = 0.86, Specificity: AUCROC = 0.71; BHRC Sensitivity: AUCROC = 0.90, Specificity: AUCROC = 0.80, Strict Specificity: AUCROC = 0.78). Conclusions: We validated CBCL-Aff as a measure of depression in adolescents aged 8-11 years and we recommend its use with the following limitation: as parents and children disagreed on the child's symptoms, we discuss implications of using a parent-report only measure of child depression.
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