ArticleFrontiers in endocrinology2025
Propensity score-matched analysis of the '2+2' parathyroid strategy in total thyroidectomy with central neck dissection.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Letter to the Editor "The dynamic changes and precise classification of parathyroid function within one year after thyroid cancer surgery".International journal of surgery (London, England) · 2026Article
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Authors and funding
7 authors.
Funding
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Abstract
Objective: To evaluate the clinical efficacy of the "2+2" strategy (preserving 2 superior glands Materials and methods: A retrospective cohort of 1,099 PTC patients treated with TT+BCLND at West China Hospital (2017-2023) was analyzed. After 1:1 PSM, 592 patients (296 per group) were included. Outcomes included temporary hypoparathyroidism (THP), permanent hypoparathyroidism (PHP), and postoperative PTH, calcium (Ca), and vitamin D (VitD) levels. Logistic regression identified predictors of THP and PHP. Results: After matching, baseline characteristics were comparable. The "2+2" group had longer operative time (150 vs. 123 min, Conclusion: The "2+2" strategy increases short-term THP risk but significantly reduces long-term PHP. Rapid biochemical recovery supports the functional viability of autotransplanted glands. This approach may offer a safe and effective strategy for parathyroid management in high-risk thyroid surgeries.
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