Evidence map›Paper›PMID 40979551›Full record

ReviewJournal of diabetes and metabolic disorders2025

Revolutionizing diabetic foot ulcer treatment: phage therapy as a next-generation antimicrobial approach- a review on breaking the cycle of resistance.

Sakshi Madaan, Ishwerpreet Kaur Jawanda, Kashish Madaan, Jasleen Kaur, Ridhi, Sharnya Pathak, Seema Kumari

Abstract readReview
In one paragraph

Review in Journal of diabetes and metabolic disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sakshi MadaanDepartment of Microbiology, Panjab University, Sector- 25, Chandigarh, 160014 India.
Ishwerpreet Kaur JawandaDepartment of Microbiology, Panjab University, Sector- 25, Chandigarh, 160014 India.
Kashish MadaanDepartment of Microbiology, Panjab University, Sector- 25, Chandigarh, 160014 India.
Jasleen KaurDepartment of Microbiology, Panjab University, Sector- 25, Chandigarh, 160014 India.
RidhiDepartment of Microbiology, Panjab University, Sector- 25, Chandigarh, 160014 India.
Sharnya PathakDepartment of Microbiology, Panjab University, Sector- 25, Chandigarh, 160014 India.
Seema KumariDepartment of Microbiology, Panjab University, Sector- 25, Chandigarh, 160014 India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diabetic foot ulcers (DFUs) are a major complication of diabetes, impacting approximately one-third of diabetic patients worldwide. Treating DFUs has become increasingly difficult due to the rise of multidrug-resistant bacteria like Results: Evidence from laboratory studies, animal models, and early clinical research shows that phage therapy is effective in targeting drug-resistant bacteria involved in DFUs. Phages offer several advantages, including their ability to specifically target harmful bacteria, break down biofilms, and multiply at infection sites. These characteristics make them a promising tool for treating chronic, non-healing wounds. Conclusion: Bacteriophage therapy represents a cutting-edge strategy for managing DFUs, particularly in cases where conventional antibiotics fail. By utilizing the natural antibacterial properties of phages, this approach could lead to more personalized and precise wound care, potentially transforming the way chronic diabetic ulcers are treated.

Indexed as

Antibiotic resistanceBacteriophage therapyBiofilmsDiabetesDiabetic foot ulcers (DFUs)Phage enzymesPseudomonas aeruginosaStaphylococcus aureus

Identifiers

PMID40979551
PMCPMC12446184

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.