Evidence map›Paper›PMID 40979450›Full record

ArticleLancet regional health. Americas2025

Three versus six sessions of problem-solving training with or without boosters for care partners of adults with dementia (CaDeS): a randomised controlled optimization trial.

Shannon B Juengst, Alexandra Holland, Kristin Wilmoth, Matthew Lee Smith, Gang Han, Charlene Supnet-Bell, Chung Lin Novelle Kew, Alka Khera, Gladys Maestre

Registry-linked trialAbstract read
In one paragraph

Article in Lancet regional health. Americas, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04748666 (Problem Solving Training), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04748666 nacompletednot on this map

Problem Solving Training (PST) for English- and Spanish-speaking Care Partners of Adults With Alzheimer's and Alzheimer'S-related Dementia

TypeinterventionalSponsorUniversity of Texas Southwestern Medical CenterRan2021 to 2023Enrolled94ConditionsAlzheimer Disease, Frontotemporal Degeneration (FTD), Lewy Body Dementia (LBD), Vascular Contributions to Cognitive Impairment and Dementia (VCID)ArmsProblem Solving Training
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shannon B JuengstBrain Injury Research Center, TIRR Memorial Hermann, Houston, TX, USA.
Alexandra HollandDepartment of Physical Medicine & Rehabilitation, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Kristin WilmothDepartment of Physical Medicine & Rehabilitation, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Matthew Lee SmithDepartment of Health Behavior, School of Public Health, Texas A&M University, College Station, TX, USA.
Gang HanCenter for Community Health and Aging, Texas A&M University, College Station, TX, USA.
Charlene Supnet-BellDepartment of Neurology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
Chung Lin Novelle KewCenter for Community Health and Aging, Texas A&M University, College Station, TX, USA.
Alka KheraDepartment of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Gladys MaestreSchool of Medicine, University of Texas Rio Grande Valley, Brownsville, TX, USA.

Funding

Rio Grande Valley Alzheimer's Resource Center for Minority Aging Research: Partnerships for ProgressP30AG059305 · NIA · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI Gladys E. Maestre · 2018 to 2026
$5.8M
HEALTH OF OLDER MINORITIEST32AG000270 · NIA · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI Brian Gregory Downer, NEIL MEHTA · 1999 to 2026
$5.2M
NIA NIH HHS P30 AG059305NIA NIH HHS T32 AG000270
6 · The paper itself

Abstract

Background: Problem-Solving Training/Descubriendo Soluciones Juntos (PST/DSJ) can improve emotional consequences of caregiving. We assessed the number of sessions and boosters needed for reducing caregiver burden and depressive symptoms among Alzheimer's disease and related dementias (ADRD) care partners. Methods: We conducted a randomised factorial-design trial of bilingual PST/DSJ among ADRD care partners (NCT04748666). Participants were randomly assigned (blocks of 8 stratified by language) to 3 PST/DSJ sessions with (n = 19) or without (n = 21) boosters or 6 PST/DSJ sessions with (n = 28) or without (n = 29) boosters. The Zarit Burden Interview measured caregiver burden and Patient Health Questionnaire (PHQ-8) measured depressive symptoms at baseline, after sessions, and after boosters. Findings: Ninety-seven care partners participated in the study (93% of those randomised) between June 2021 and July 2023 (n = 80 women, 83%). Ninety-five were included in intention-to-treat analysis (98% retention). For caregiver burden, all groups improved significantly over time (Estimate = -0.40, p = 0.004, Cohen's D = 0.31), with no difference between intervention groups. For depressive symptoms, there was a main effect of time (Estimate = -0.16, p = 0.005, Cohen's D = 0.33) indicating overall improvement regardless of group. Within group effect sizes (Cohen's D = 0.17-0.51) suggest larger improvement with 6 sessions (Cohen's D = 0.28-0.51) than 3 sessions (Cohen's D = 0.17-0.41). No adverse events occurred. Interpretation: Neither the number of sessions nor boosters resulted in differential efficacy for caregiver burden and depressive symptoms, though six sessions and boosters yielded the largest effect sizes. These results can inform the implementation of an evidence-based, bilingual problem-solving intervention to reduce burden and improve mood among diverse dementia care partners. Funding: Texas Alzheimer's Research and Care Consortium [TARCC 2020-06-25-CR].

Indexed as

Alzheimer’s disease and related dementiaCaregiverDementiaDementia careMetacognitive strategiesProblem-solvingPsychosocial intervention

Identifiers

PMID40979450
PMCPMC12446550

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.