Evidence map›Paper›PMID 40979362›Full record

ArticleFrontiers in veterinary science2025

Yuting Li, Liping Zhu, Dongsheng He, Ling Fang, Yajing Li, Shusheng Tang

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuting LiNational Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China.
Liping ZhuZhucheng Haotian Pharm Co., Ltd, Zhucheng, China.
Dongsheng HeZhucheng Haotian Pharm Co., Ltd, Zhucheng, China.
Ling FangZhucheng Haotian Pharm Co., Ltd, Zhucheng, China.
Yajing LiZhucheng Haotian Pharm Co., Ltd, Zhucheng, China.
Shusheng TangNational Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Methods: The safety of SREC was assessed through a series of tests, including acute oral toxicity in mice and rats, a 90-day subchronic toxicity test in rats, genotoxicity assays (Ames test, mouse bone marrow micronucleus test, and mouse sperm abnormality test), and teratogenicity evaluation in pregnant rats. Results: The acute oral toxicity test indicated that the LD₅₀ of SREC in mice and rats was greater than 5,000 mg/kg body weight. In the 90-day subchronic toxicity test, SREC was non-toxic at doses up to 50,000 mg/kg in feed. The Ames test showed no mutagenic effects on Discussion: SREC exhibited low toxicity in both acute and subchronic tests, and no evidence of genotoxicity or teratogenicity was observed. These findings suggest that SREC is safe as a potential feed additive and provide valuable reference data for its safety evaluation.

Indexed as

genotoxicityoral acute toxicitStevia rebaudiana extractsub chronic toxicityteratogenicity

Identifiers

PMID40979362
PMCPMC12444892

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.