Evidence map›Paper›PMID 40979254›Full record

ArticleJournal of biomedical optics2025

Noninvasive continuous blood pressure prediction using FlexNIRS and machine learning during carotid endarterectomy.

Zahra Einalou, Mehrdad Dadgostar, Kuan-Cheng Wu, Alyssa Martin, Mitchell B Robinson, Marco Renna, Jason Z Qu, John Sunwoo, Maria Angela Franceschini

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zahra EinalouMassachusetts General Hospital, Harvard Medical School, Athinoula A. Martinos Center for Biomedical Imaging, Boston, Massachusetts, United States.
Mehrdad DadgostarMassachusetts General Hospital, Harvard Medical School, Athinoula A. Martinos Center for Biomedical Imaging, Boston, Massachusetts, United States.
Kuan-Cheng WuMassachusetts General Hospital, Harvard Medical School, Athinoula A. Martinos Center for Biomedical Imaging, Boston, Massachusetts, United States.
Alyssa MartinMassachusetts General Hospital, Harvard Medical School, Athinoula A. Martinos Center for Biomedical Imaging, Boston, Massachusetts, United States.
Mitchell B RobinsonMassachusetts General Hospital, Harvard Medical School, Athinoula A. Martinos Center for Biomedical Imaging, Boston, Massachusetts, United States.ORCID https://orcid.org/0000-0001-5810-0459
Marco RennaMassachusetts General Hospital, Harvard Medical School, Athinoula A. Martinos Center for Biomedical Imaging, Boston, Massachusetts, United States.ORCID https://orcid.org/0000-0002-6642-7360
Jason Z QuMassachusetts General Hospital, Harvard Medical School, Department of Anesthesia, Critical Care and Pain Medicine, Boston, Massachusetts, United States.
John SunwooMassachusetts General Hospital, Harvard Medical School, Athinoula A. Martinos Center for Biomedical Imaging, Boston, Massachusetts, United States.ORCID https://orcid.org/0000-0003-4314-7232
Maria Angela FranceschiniMassachusetts General Hospital, Harvard Medical School, Athinoula A. Martinos Center for Biomedical Imaging, Boston, Massachusetts, United States.ORCID https://orcid.org/0000-0001-6758-423X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: Continuous blood pressure (BP) monitoring is crucial for maintaining hemodynamic stability and complication prevention. Near-infrared spectroscopy photoplethysmography (NIRS-PPG) offers a noninvasive alternative to arterial lines (A-line) for continuous BP monitoring. Aim: We aim to assess whether a wearable NIRS-PPG device (FlexNIRS) can estimate mean arterial pressure (MAP) using linear and Gaussian process regression (GPR) models. Approach: NIRS-PPG signals were recorded bilaterally in 10 patients undergoing carotid endarterectomy. Subject-specific linear regression and GPR models predicted MAP based on heart rate and peak features of the NIRS-PPG signal. A-line readings served as the reference. Results: All models achieved strong performance with Conclusions: This preliminary study supports the feasibility of noninvasive MAP estimation using NIRS-PPG and machine learning. The approach may provide a practical alternative for BP monitoring after A-line removal in postoperative and intensive care unit settings.

Indexed as

Blood PressureBlood Pressure DeterminationEndarterectomy, CarotidMachine LearningPhotoplethysmographyAgedAged, 80 and overFemaleHumansLinear ModelsMaleMiddle AgedSignal Processing, Computer-AssistedSpectroscopy, Near-InfraredWearable Electronic Devicescarotid endarterectomyFlexNIRSGaussian process regressionlinear regression modelnear-infrared spectroscopy photoplethysmographynoninvasive blood pressure monitoring

Identifiers

PMID40979254
PMCPMC12447979

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.