ArticleFrontiers in neurology2025
Regional differences in the incidence of Alzheimer's disease and related dementias in South Carolina.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Hospitalizations and long-term care for older adults with Alzheimer's disease and related dementia: Differences across geographic regions of the United States.Journal of Alzheimer's disease : JAD · 2026Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: There is an increase in the population of older adults, 65 years or older in South Carolina. Socio economic and environmental factors are linked to the diagnosis of Alzheimer's Disease and related dementias (ADRD). The aim of this study was therefore, to characterize the incidence of ADRD by public health regions (PHR). Methods: We estimated the incidence of ADRD for 2021using data from South Carolina Alzheimer's Disease Registry (SCADR) and the Annual County Resident Population Estimates (ACRPE). The incidence of new cases per 100, 0000 population for each county, and PHR, and age-adjusted ADRD specific diagnosis were estimated. Poisson regression modeling was used to compare crude and ADRD specific incidence by PHRs. The incidence of ADRD by counties and PHRs was visualized using TIGERline files. Results: A total of 18,955 registrants from the SCADR were included in this study. About 38% of the participants were between 75 and 84 years. Additionally, about 79% of the registrants had Alzheimer's (AD) diagnosis. The crude incidence of ADRD was higher in the Pee Dee PHR (896 per 100,000). Among ADRD specific diagnosis, AD incidence was higher in the Pee Dee PHR (727 per 100,000), Vascular dementia (VaD) and Mixed dementia incidences were higher in the Upstate PHR. The crude incidence of ADRD differed significantly across all the PHRs ( Discussion: Regional differences in the incidence of ADRD suggest possible disparities in healthcare access, socioeconomic conditions and geographical factors. Targeted interventions, and early screening among young populations should be prioritized.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.