Evidence map›Paper›PMID 40979174›Full record

ArticleClinical and translational radiation oncology2025

Trends in use of magnetic resonance imaging and partial breast irradiation between 2011-2022 in the Netherlands: A population-based study.

Y A Civil, A H Eijkelboom, A E Veldink, M C van Maaren, J H Maduro, K M Duvivier, S Siesling, H J G D van den Bongard

Abstract read
In one paragraph

Article in Clinical and translational radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

Y A CivilAmsterdam UMC location Vrije Universiteit Amsterdam, Department of Radiation Oncology, Amsterdam, the Netherlands.
A H EijkelboomNetherlands Comprehensive Cancer Organisation (IKNL), Department of Research and Development, Utrecht, the Netherlands.
A E VeldinkNetherlands Comprehensive Cancer Organisation (IKNL), Department of Research and Development, Utrecht, the Netherlands.
M C van MaarenNetherlands Comprehensive Cancer Organisation (IKNL), Department of Research and Development, Utrecht, the Netherlands.
J H MaduroUniversity of Groningen, University Medical Center Groningen, Department of Radiation Oncology, Groningen, the Netherlands.
K M DuvivierAmsterdam UMC location Vrije Universiteit Amsterdam, Department of Radiology, Amsterdam, the Netherlands.
S SieslingNetherlands Comprehensive Cancer Organisation (IKNL), Department of Research and Development, Utrecht, the Netherlands.
H J G D van den BongardAmsterdam UMC location Vrije Universiteit Amsterdam, Department of Radiation Oncology, Amsterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to investigate whether the introduction of partial breast irradiation (PBI) was associated with increased MRI use in the Netherlands from 2011 to 2022, and examined the impact of MRI on treatment and outcomes. Methods: Women aged ≥50 who underwent surgery (without preoperative systemic therapy) for cT1-2N0M0 breast cancer or DCIS between 2011 and 2022 were selected from the Netherlands Cancer Registry. Logistic regression was used to analyze associations between MRI and treatment or surgical radicality, stratified by tumour type. Subgroup analyses were performed in patients meeting ASTRO PBI criteria (unifocal cT1, grade 1/2, ER-positive, pure DCIS ≤ 2,5 cm). Results: Among 119,768 patients, 35,863 (30 %) received MRI, increasing from 24 % (2011) to 37 % (2022). PBI use increased from 3 % (2017) to 21 % (2022). MRI was not associated with the probability of receiving PBI (OR 0.98, 95 % CI:0.90-1.07). In patients with invasive breast cancer, MRI was associated with fewer DCIS-involved margins (OR 0.81, 95 % CI:0.74-0.89), but a higher probability of mastectomy (OR 1.29, 95 % CI:1.24-1.34). In patients with an ASTRO-defined PBI indication, MRI use was associated with a decreased likelihood of receiving PBI in invasive cancer (OR:0.66, 95 % CI:0.60-0.72) and DCIS (OR:0.80, 95 % CI:0.75-0.85). Conclusion: This study shows rising trends in PBI and MRI use in the Netherlands from 2011 to 2022. MRI reduced PBI eligibility and enhanced surgical precision by less involved margins in patients with cT1N0 breast cancer without PST.

Indexed as

Invasive breast cancerMRINational trendsPartial breast irradiation

Identifiers

PMID40979174
PMCPMC12444457

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