ArticleCureus2025
Intracranial Pressure-Guided Therapy in 3,4-Methylenedioxymethamphetamine (MDMA)-Induced Cerebral Edema: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Rare but relevant: MDMA and hyponatraemia.Addiction (Abingdon, England) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
3,4-Methylenedioxymethamphetamine (MDMA), commonly called ecstasy, is a synthetic stimulant popular among young adults. Although its psychoactive effects are sought after, MDMA can lead to serious complications, including neurological and cardiovascular crises. Severe toxicity, although uncommon, may result in cerebral edema, hyponatremia, seizures, or death. We describe the case of a 21-year-old woman who collapsed after taking MDMA and drinking large volumes of water. On arrival at the hospital, she was found to have significant cerebral edema and low sodium. After endotracheal intubation and transfer to a tertiary center, she was managed with intracranial pressure (ICP) monitoring and careful correction of hyponatremia. She made a full recovery and was discharged from intensive care within four days. This report highlights how ICP-guided management can help optimize care and reduce risks in patients with MDMA-related cerebral edema.
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Registered trials
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