Evidence map›Paper›PMID 40978993›Full record

ArticleCureus2025

Echocardiography-Unmasked Pulmonary Hypertension in Acute Respiratory Distress Syndrome (ARDS): A Fatal Case of Biventricular Failure.

Mohamed M Dar, Ihab Nagla, Ramy Kishk

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mohamed M DarCritical Care Medicine Department, Imperial College Healthcare National Health Service (NHS) Trust, London, GBR.
Ihab NaglaCritical Care Department, Imperial College Healthcare National Health Service (NHS) Trust, London, GBR.
Ramy KishkCritical Care Department, Faculty of Medicine, Cairo University, Cairo, EGY.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of a 65-year-old hypertensive male patient admitted to the ICU with altered consciousness, shock, and profound hypoxemia. He met the Berlin criteria for severe acute respiratory distress syndrome (ARDS) and was intubated immediately. Despite mechanical ventilation and vasopressor support (norepinephrine 3.5 µg/kg/min), oxygenation remained critically impaired (partial pressure of arterial oxygen/fraction of inspired oxygen (PaO₂/FiO₂) ratio: 50 mmHg). Early bedside transthoracic echocardiography revealed severe pulmonary hypertension (PH) (pulmonary artery systolic pressure (PASP): 85 mmHg), reduced right ventricular function (tricuspid annular plane systolic excursion (TAPSE): 1.5 cm), and left ventricular systolic dysfunction (left ventricular ejection fraction (LVEF): 30%), indicating acute cor pulmonale and biventricular failure. The patient's course was marked by refractory multiorgan failure, including acute renal injury and neurologic unresponsiveness. Despite full supportive measures, he died within 30 days of admission. This case emphasizes the prognostic value of early echocardiographic assessment in ARDS. Identifying elevated pulmonary pressures and biventricular dysfunction early may aid in risk stratification, guide management, and potentially improve outcomes in critically ill patients.

Indexed as

acute respiratory distress syndromebiventricular failurepulmonary hypertensionright ventricular dysfunctiontransthoracic echocardiography

Identifiers

PMID40978993
PMCPMC12444732

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.