ArticleCureus2025
Under the Radar: Back Pain and Acute Kidney Injury as Harbingers of Type A Aortic Dissection.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aortic dissection is a catastrophic vascular emergency with a high mortality rate if not diagnosed and managed in a timely manner. The classic presentation of thoracic aortic dissection includes the sudden onset of severe chest pain radiating to the back. Still, it may also present with atypical symptoms and signs of end-organ vascular compromise. We present a case of a 57-year-old female with a medical history of hypertension with poor medication adherence, major depressive disorder, chronic low back pain, and cocaine use disorder, who initially presented to the ED with worsening chronic low back pain, which was attributed to a musculoskeletal origin. She received analgesics, which improved the pain. Approximately 7 hours after presentation, the following morning, the patient developed acute-onset chest pain, prompting repeat evaluation, including an electrocardiogram and cardiac biomarkers, which revealed T-wave inversion in the lateral leads and elevated troponin levels. Based on these findings, the non-ST elevation myocardial infarction (NSTEMI) protocol was initiated. While the back pain and chest pain improved, her kidney function continued to rapidly deteriorate from the time of admission, prompting the team to perform a sonogram and subsequently an abdominal CT, which revealed a heterogeneous, hyperechoic right kidney with loss of corticomedullary distinction and possible aortic pathology. A CT angiogram of the chest, abdomen, and pelvis confirmed a type A aortic dissection extending from the aortic root to the iliac bifurcation. The dissection caused significant narrowing at the origin of the left common carotid artery and partial infarction of the right kidney due to involvement of the renal artery. The patient was transferred to a tertiary hospital for surgical intervention and remained hemodynamically stable; however, she opted against surgical intervention and left against medical advice despite extensive counseling. Clinicians should maintain a high index of suspicion for aortic dissection in patients with unexplained back pain, particularly when there are signs of multiorgan ischemia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.