Evidence map›Paper›PMID 40978964›Full record

ArticleCureus2025

Under the Radar: Back Pain and Acute Kidney Injury as Harbingers of Type A Aortic Dissection.

Yohannes Debebe Gelan, Mark Ntow, Samuel Sule-Saa, Ajibola Adedayo

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yohannes Debebe GelanInternal Medicine, Interfaith Medical Center, Brooklyn, USA.
Mark NtowInternal Medicine, Interfaith Medical Center, Brooklyn, USA.
Samuel Sule-SaaInternal Medicine, Interfaith Medical Center, Brooklyn, USA.
Ajibola AdedayoCardiology, Interfaith Medical Center, Brooklyn, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aortic dissection is a catastrophic vascular emergency with a high mortality rate if not diagnosed and managed in a timely manner. The classic presentation of thoracic aortic dissection includes the sudden onset of severe chest pain radiating to the back. Still, it may also present with atypical symptoms and signs of end-organ vascular compromise. We present a case of a 57-year-old female with a medical history of hypertension with poor medication adherence, major depressive disorder, chronic low back pain, and cocaine use disorder, who initially presented to the ED with worsening chronic low back pain, which was attributed to a musculoskeletal origin. She received analgesics, which improved the pain. Approximately 7 hours after presentation, the following morning, the patient developed acute-onset chest pain, prompting repeat evaluation, including an electrocardiogram and cardiac biomarkers, which revealed T-wave inversion in the lateral leads and elevated troponin levels. Based on these findings, the non-ST elevation myocardial infarction (NSTEMI) protocol was initiated. While the back pain and chest pain improved, her kidney function continued to rapidly deteriorate from the time of admission, prompting the team to perform a sonogram and subsequently an abdominal CT, which revealed a heterogeneous, hyperechoic right kidney with loss of corticomedullary distinction and possible aortic pathology. A CT angiogram of the chest, abdomen, and pelvis confirmed a type A aortic dissection extending from the aortic root to the iliac bifurcation. The dissection caused significant narrowing at the origin of the left common carotid artery and partial infarction of the right kidney due to involvement of the renal artery. The patient was transferred to a tertiary hospital for surgical intervention and remained hemodynamically stable; however, she opted against surgical intervention and left against medical advice despite extensive counseling. Clinicians should maintain a high index of suspicion for aortic dissection in patients with unexplained back pain, particularly when there are signs of multiorgan ischemia.

Indexed as

acsacute coronary syndromeacute kidney injurylow back pain (lbp)systemic hypertensiontype a aortic dissection

Identifiers

PMID40978964
PMCPMC12448148

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